The Novel Histone Deacetylase Inhibitor, OBP-801, Induces Apoptosis in Rhabdoid Tumors by Releasing the Silencing of

Animals Apoptosis Female Histone Deacetylase Inhibitors / pharmacology Humans Mice Mice, Nude Proto-Oncogene Proteins c-bcl-2 / metabolism Rhabdoid Tumor / drug therapy

Journal

Molecular cancer therapeutics
ISSN: 1538-8514
Titre abrégé: Mol Cancer Ther
Pays: United States
ID NLM: 101132535

Informations de publication

Date de publication:
10 2020
Historique:
received: 30 03 2020
revised: 03 06 2020
accepted: 07 08 2020
pubmed: 28 8 2020
medline: 7 8 2021
entrez: 28 8 2020
Statut: ppublish

Résumé

Rhabdoid tumor is an aggressive, early childhood tumor. Biallelic inactivation of the SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (

Identifiants

DOI: 10.1158/1535-7163.MCT-20-0243 PMID: 32847975
pubmed: 32847975
pii: 1535-7163.MCT-20-0243
doi: 10.1158/1535-7163.MCT-20-0243
doi:

Substances chimiques

Histone Deacetylase Inhibitors 0
PMAIP1 protein, human 0
Proto-Oncogene Proteins c-bcl-2 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1992-2000

Informations de copyright

©2020 American Association for Cancer Research.

Auteurs

Yohei Sugimoto (Y)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

Yoshiki Katsumi (Y)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

Tomoko Iehara (T)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan. iehara@koto.kpu-m.ac.jp.
ORCID: 0000-0003-1740-7096

Daisuke Kaneda (D)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.
Department of Pediatrics, Japan Community Health care Organization (JCHO), Kobe Central Hospital, Kobe, Hyogo, Japan.
ORCID: 0000-0002-7067-6263

Chihiro Tomoyasu (C)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.
Department of Pediatrics, Kyoto City Hospital, Nakagyo Ward, Kyoto, Japan.

Kazutaka Ouchi (K)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

Hideki Yoshida (H)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

Mitsuru Miyachi (M)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

Shigeki Yagyu (S)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.
ORCID: 0000-0003-4256-9783

Ken Kikuchi (K)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.
ORCID: 0000-0003-3097-7480

Kunihiko Tsuchiya (K)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

Yasumichi Kuwahara (Y)

Department of Biochemistry and Molecular Biology, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

Toshiyuki Sakai (T)

Department of Drug Discovery Medicine, Kyoto Prefectural University of Medicine Kamigyo-ku, Kyoto, Japan.

Hajime Hosoi (H)

Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The Novel Histone Deacetylase Inhibitor,...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › The Novel Histone Deacetylase Inhibitor,...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de désacétylase d'histone › The Novel Histone Deacetylase Inhibitor,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Novel Histone Deacetylase Inhibitor,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › The Novel Histone Deacetylase Inhibitor,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souches mutantes de souris › Souris nude › The Novel Histone Deacetylase Inhibitor,...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › Protéines oncogènes › Protéines proto-oncogènes › Protéines proto-oncogènes c-bcl-2 › The Novel Histone Deacetylase Inhibitor,...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs complexes et mixtes › Tumeur rhabdoïde › The Novel Histone Deacetylase Inhibitor,...