Evaluation of Cysteine Protease C of Leishmania donovani in Comparison with Glycoprotein 63 and Elongation Factor 1α for Diagnosis of Human Visceral Leishmaniasis and for Posttreatment Follow-Up Response.
diagnosis
immunology
infection
leishmaniasis
parasitology
recombinant antigens
Journal
Journal of clinical microbiology
ISSN: 1098-660X
Titre abrégé: J Clin Microbiol
Pays: United States
ID NLM: 7505564
Informations de publication
Date de publication:
21 10 2020
21 10 2020
Historique:
received:
04
02
2020
accepted:
30
07
2020
pubmed:
28
8
2020
medline:
24
6
2021
entrez:
28
8
2020
Statut:
epublish
Résumé
Visceral leishmaniasis (VL) is a threat in many developing countries. Much effort has been put to eliminating this disease, for which serodiagnosis remains the mainstay for VL control programs. New and improved antigens as diagnostic candidates are required, though, as the available antigens fail to demonstrate equal optimum performance in all areas of endemicity. Moreover, these diagnoses are dependent on invasive serum sampling. In the current study, we cloned and expressed
Identifiants
pubmed: 32848039
pii: JCM.00213-20
doi: 10.1128/JCM.00213-20
pmc: PMC7587114
pii:
doi:
Substances chimiques
Antibodies, Protozoan
0
Antigens, Protozoan
0
Glycoproteins
0
Peptide Elongation Factor 1
0
Cysteine Proteases
EC 3.4.-
Cysteine
K848JZ4886
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Medical Research Council
ID : MR/P027989/1
Pays : United Kingdom
Informations de copyright
Copyright © 2020 American Society for Microbiology.
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