A Cross-Sectional Study on Central Sensitization and Autonomic Changes in Fibromyalgia.
autonomic dysfunction
cold pressor test
cortical sensitization
deep breathing test
functional near-infrared spectroscopy
heart rate variability
Journal
Frontiers in neuroscience
ISSN: 1662-4548
Titre abrégé: Front Neurosci
Pays: Switzerland
ID NLM: 101478481
Informations de publication
Date de publication:
2020
2020
Historique:
received:
18
03
2020
accepted:
06
07
2020
entrez:
28
8
2020
pubmed:
28
8
2020
medline:
28
8
2020
Statut:
epublish
Résumé
Fibromyalgia is a multi-symptomatic disorder characterized by generalized pain. The pathophysiology of fibromyalgia is supposedly an interplay between central nervous system hyper-responsiveness, autonomic dysfunction, and peripheral pain. In this cross-sectional study, the objective was to assess central sensitization and autonomic activity in patients with fibromyalgia compared with control. Fifty adults diagnosed with fibromyalgia by the modified American College of Rheumatology 2010 criteria and an equal number of age- and sex-matched controls participated in the study in an urban tertiary care hospital. Central sensitization was assessed by history and by evidence of increased prefrontal cortical activity as measured by cortical oxygenation using functional near-infrared spectroscopy. Autonomic activity was assessed by heart rate variability, electrodermal activity, and deep breathing test in three physiological states: rest, sympathetic stress (cold pressor test), and deep breathing. Mann-Whitney
Identifiants
pubmed: 32848561
doi: 10.3389/fnins.2020.00788
pmc: PMC7417433
doi:
Types de publication
Journal Article
Langues
eng
Pagination
788Informations de copyright
Copyright © 2020 Hazra, Venkataraman, Handa, Yadav, Wadhwa, Singh, Kochhar, Deepak and Sarkar.
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