Evaluating Thymic Function After Human Hematopoietic Stem Cell Transplantation in the Personalized Medicine Era.

Hematopoietic Stem Cell Transplantation / methods Humans Lymphopoiesis / immunology Precision Medicine / methods Thymus Gland / immunology
T-cells TREC hematopoietic stem cell transplantation immune reconstitution thymic function thymus

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2020
Historique:
received: 11 03 2020
accepted: 26 05 2020
entrez: 28 8 2020
pubmed: 28 8 2020
medline: 7 4 2021
Statut: epublish

Résumé

Hematopoietic stem cell transplantation (HSCT) is an effective treatment option for several malignant and non-malignant hematological diseases. The clinical outcome of this procedure relies to a large extent on optimal recovery of adaptive immunity. In this regard, the thymus plays a central role as the primary site for

Identifiants

DOI: 10.3389/fimmu.2020.01341 PMID: 32849495 PMC: PMC7412601
pubmed: 32849495
doi: 10.3389/fimmu.2020.01341
pmc: PMC7412601
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1341

Informations de copyright

Copyright © 2020 Gaballa, Clave, Uhlin, Toubert and Arruda.

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Auteurs

Ahmed Gaballa (A)

Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

Emmanuel Clave (E)

INSERM UMR-1160, Institut de Recherche Saint-Louis, Hôpital Saint-Louis APHP, Paris, France.
Université de Paris, Paris, France.

Michael Uhlin (M)

Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Department of Applied Physics, Science for Life Laboratory, Royal Institute of Technology, Stockholm, Sweden.
Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden.

Antoine Toubert (A)

INSERM UMR-1160, Institut de Recherche Saint-Louis, Hôpital Saint-Louis APHP, Paris, France.
Université de Paris, Paris, France.

Lucas C M Arruda (LCM)

Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

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Classifications MeSH

questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation cellulaire › Transplantation de cellules souches › Transplantation de cellules souches hématopoïétiques › Evaluating Thymic Function After Human...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Evaluating Thymic Function After Human...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hématopoïèse › Leucopoïèse › Lymphopoïèse › Evaluating Thymic Function After Human...
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › Evaluating Thymic Function After Human...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Thymus (glande) › Evaluating Thymic Function After Human...