Does the Oral Microbiome Play a Role in Hypertensive Pregnancies?

beetroot juice blood pressure dietary nitrate hypertension nitric oxide nitrite oral microbiota pregnancy

Journal

Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359

Informations de publication

Date de publication:
2020
Historique:
received: 04 03 2020
accepted: 25 06 2020
entrez: 28 8 2020
pubmed: 28 8 2020
medline: 22 6 2021
Statut: epublish

Résumé

Chronic hypertension during gestation is associated with an increased risk of adverse pregnancy outcomes including pre-eclampsia, fetal growth restriction and preterm birth. Research into new chemotherapeutic regimes for the treatment of hypertension in pregnancy is limited due to concerns about fetal toxicity and teratogenicity, and new therapeutic avenues are being sought in alternative physiological pathways. Historically, generation of the vasodilator nitric oxide was believed to be solely from

Identifiants

pubmed: 32850488
doi: 10.3389/fcimb.2020.00389
pmc: PMC7406642
doi:

Substances chimiques

Nitrates 0
Nitrites 0
Nitric Oxide 31C4KY9ESH

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

389

Informations de copyright

Copyright © 2020 Willmott, McBain, Humphreys, Myers and Cottrell.

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Auteurs

Thomas Willmott (T)

Maternal and Fetal Health Research Centre, Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.
Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.

Andrew J McBain (AJ)

Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.

Gavin J Humphreys (GJ)

Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.

Jenny Myers (J)

Maternal and Fetal Health Research Centre, Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.

Elizabeth Cottrell (E)

Maternal and Fetal Health Research Centre, Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.

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Classifications MeSH