Clinical, Imaging and Procedural Risk Factors for Intrauterine Infective Complications After Uterine Fibroid Embolisation: A Retrospective Case Control Study.
Adult
Body Mass Index
Case-Control Studies
Diagnostic Imaging
Embolization, Therapeutic
/ adverse effects
Female
Humans
Hysterectomy
Infections
/ etiology
Leiomyoma
/ pathology
Middle Aged
Multivariate Analysis
Obesity
Retrospective Studies
Risk Factors
Uterine Diseases
/ etiology
Uterine Neoplasms
/ therapy
Uterus
/ anatomy & histology
Endometritis
Fibroids
Infection
Uterine fibroid embolisation
Journal
Cardiovascular and interventional radiology
ISSN: 1432-086X
Titre abrégé: Cardiovasc Intervent Radiol
Pays: United States
ID NLM: 8003538
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
23
04
2020
accepted:
05
08
2020
pubmed:
28
8
2020
medline:
17
4
2021
entrez:
28
8
2020
Statut:
ppublish
Résumé
This was a retrospective case-control study at a single tertiary centre investigating all UFE procedures between January 2013 and December 2018 for symptomatic fibroids. The aim was to determine the clinical, imaging and procedural risk factors which impact upon the risk of post-uterine fibroid embolisation (UFE) intrauterine infection. Cases were patients which developed intrauterine infection post-procedure, and controls were the background UFE population without infection. Clinical demographics, presenting symptoms, uterine and fibroid characteristics on imaging and procedural variants were analysed. A p value of less than 0.05 was considered statistically significant. The main outcome measures were presence of infection and requirement of emergency hysterectomy. 333 technically successful UFE procedures were performed in 330 patients. Infection occurred after 25 procedures (7.5%). 3 of these patients progressed to overwhelming sepsis and required emergency hysterectomy. Clinical obesity (BMI > 30) (OR 1.53 [1.18-1.99]) and uterine volume > 1000cm3 (2.94 [1.15-7.54]) were found to increase the risk of infection CONCLUSIONS: UFE is generally safe in patients with symptomatic fibroids. Obese patients (BMI > 30) and those with large volume uteri (> 1000cm
Identifiants
pubmed: 32851424
doi: 10.1007/s00270-020-02622-2
pii: 10.1007/s00270-020-02622-2
pmc: PMC7649153
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1910-1917Références
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