Facial nerve paralysis in malignant otitis externa: comparison of the clinical and paraclinical findings.
Malignant otitis externa
facial nerve involvement
facial paralysis
prognosis
skull base osteomyelitis
Journal
Acta oto-laryngologica
ISSN: 1651-2251
Titre abrégé: Acta Otolaryngol
Pays: England
ID NLM: 0370354
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
pubmed:
28
8
2020
medline:
11
9
2021
entrez:
28
8
2020
Statut:
ppublish
Résumé
Malignant otitis externa is an uncommon but critical challenging disease with some degree of cranial nerve involvement. to examine the factors leading to facial paralysis in these patients and clarify indications for aggressive treatment in the group most at risk. In a case-control study, demographic, clinical, laboratory, audiometric, imaging, and treatment characteristics of 139 patients in groups with and without facial paralysis were analysed. 45 patients (32.4%) had facial paralysis. Compared to patients without facial nerve involvement, patients with facial palsy had a higher rate of inflammatory markers (mean erythrocyte sedimentation rate on admission [67.71 vs 51.16 mm/h], and the average of total ESR [64.27 vs 54.46 mm/h], as well as the mean C-reactive protein [38.96 vs 27.53 mg/L]). Also, the involvement of the facial canal ( Nasopharyngeal extension of the inflammation and facial nerve canal erosion might be useful as predictors of facial nerve dysfunction. The elevated erythrocyte sedimentation rate is correlated with the increased risk of facial paralysis, and aggressive medical management is more crucial. Improvement in predicting the outcome of patients with malignant otitis externa.
Sections du résumé
BACKGROUND
BACKGROUND
Malignant otitis externa is an uncommon but critical challenging disease with some degree of cranial nerve involvement.
AIM/OBJECTIVE
OBJECTIVE
to examine the factors leading to facial paralysis in these patients and clarify indications for aggressive treatment in the group most at risk.
MATERIAL AND METHODS
METHODS
In a case-control study, demographic, clinical, laboratory, audiometric, imaging, and treatment characteristics of 139 patients in groups with and without facial paralysis were analysed.
RESULTS
RESULTS
45 patients (32.4%) had facial paralysis. Compared to patients without facial nerve involvement, patients with facial palsy had a higher rate of inflammatory markers (mean erythrocyte sedimentation rate on admission [67.71 vs 51.16 mm/h], and the average of total ESR [64.27 vs 54.46 mm/h], as well as the mean C-reactive protein [38.96 vs 27.53 mg/L]). Also, the involvement of the facial canal (
CONCLUSION
CONCLUSIONS
Nasopharyngeal extension of the inflammation and facial nerve canal erosion might be useful as predictors of facial nerve dysfunction. The elevated erythrocyte sedimentation rate is correlated with the increased risk of facial paralysis, and aggressive medical management is more crucial.
SIGNIFICANCE
CONCLUSIONS
Improvement in predicting the outcome of patients with malignant otitis externa.
Identifiants
pubmed: 32852248
doi: 10.1080/00016489.2020.1808242
doi:
Substances chimiques
Anti-Bacterial Agents
0
Antifungal Agents
0
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM