Respiratory Failure in a Child With Pulmonary Metastatic Osteosarcoma and COVID-19.


Journal

Journal of pediatric hematology/oncology
ISSN: 1536-3678
Titre abrégé: J Pediatr Hematol Oncol
Pays: United States
ID NLM: 9505928

Informations de publication

Date de publication:
01 08 2021
Historique:
received: 18 05 2020
accepted: 25 06 2020
pubmed: 28 8 2020
medline: 27 8 2021
entrez: 28 8 2020
Statut: ppublish

Résumé

The novel coronavirus, SARS-CoV-2, causes much more severe disease in adults than in children. Although it is anticipated that immune compromised children and children with cancer may be at higher risk of developing severe or fatal COVID-19, there are no currently published reports of fatal disease in a child with cancer. Because of the discrepancy in disease severity between adult and pediatric patients, we report the case of an adolescent with pulmonary metastatic osteosarcoma who died of COVID-19 early in the course of the pandemic in New York City in the hope that heightening awareness that pulmonary metastatic disease may predispose to a more severe outcome will increase surveillance in this vulnerable population.

Identifiants

pubmed: 32852398
pii: 00043426-202108000-00034
doi: 10.1097/MPH.0000000000001897
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e859-e860

Informations de copyright

Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

COVID-19: Data. Available at: https://www1.nyc.gov/site/doh/covid/covid-19-data.page . Accessed April 30, 2020.
Lu X, Zhang L, Du H, et al. SARS-CoV-2 infection in children. New Engl J Med. 2020;382:1663–1665.
Balduzzi A, Brivio E, Rovelli A, et al. Lessons after the early management of the COVID-19 outbreak in a pediatric transplant and hemato-oncology center embedded within a COVID-19 dedicated hospital in Lombardia, Italy. Estote parati. Bone Marrow Transplant. 2020. Available at: https://doi.org/10.1038/s41409-020-0895-4 .
doi: 10.1038/s41409-020-0895-4
Sukumaran R, Nayak N, Mony R, et al. Osteosarcoma presenting with massive malignant pleural effusion. Oncol J India. 2019;3:20–23.
Saha D, Saha K, Banerjee A, et al. Osteosarcoma relapse as pleural metastasis. South Asian J Cancer. 2013;2:56.
Dai M, Liu D, Liu M, et al. Patients with cancer appear more vulnerable to SARS-CoV-2: a multicenter study during the COVID-19 outbreak. Cancer Disc. 2020;10:783–791.

Auteurs

Rachel Offenbacher (R)

Department of Pediatrics, Albert Einstein College of Medicine.
Division of Pediatric Hematology, Oncology and Marrow & Blood Cell Transplantation, Children's Hospital at Montefiore, Bronx, NY.

Lara Fabish (L)

Department of Pediatrics, Albert Einstein College of Medicine.
Division of Pediatric Hematology, Oncology and Marrow & Blood Cell Transplantation, Children's Hospital at Montefiore, Bronx, NY.

Alissa Baker (A)

Department of Pediatrics, Albert Einstein College of Medicine.
Division of Pediatric Hematology, Oncology and Marrow & Blood Cell Transplantation, Children's Hospital at Montefiore, Bronx, NY.

Alexander J Chou (AJ)

Department of Pediatrics, Albert Einstein College of Medicine.
Division of Pediatric Hematology, Oncology and Marrow & Blood Cell Transplantation, Children's Hospital at Montefiore, Bronx, NY.

David M Loeb (DM)

Department of Pediatrics, Albert Einstein College of Medicine.
Division of Pediatric Hematology, Oncology and Marrow & Blood Cell Transplantation, Children's Hospital at Montefiore, Bronx, NY.

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