Detection of Germline Mutations in a Cohort of 139 Patients with Bilateral Breast Cancer by Multi-Gene Panel Testing: Impact of Pathogenic Variants in Other Genes beyond

ATM BRCA1 BRCA2 CHECK2 PALB2 PTEN bilateral breast cancer breast cancer germline pathogenic variants multi-gene panel testing

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
25 Aug 2020
Historique:
received: 23 07 2020
revised: 23 08 2020
accepted: 24 08 2020
entrez: 29 8 2020
pubmed: 29 8 2020
medline: 29 8 2020
Statut: epublish

Résumé

Patients with unilateral breast cancer (UBC) have an increased risk of developing bilateral breast cancer (BBC). The annual risk of contralateral BC is about 0.5%, but increases by up to 3% in

Identifiants

pubmed: 32854451
pii: cancers12092415
doi: 10.3390/cancers12092415
pmc: PMC7564956
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Genet Med. 2014 Nov;16(11):830-7
pubmed: 24763289
Ann Oncol. 2015 Sep;26 Suppl 5:v8-30
pubmed: 26314782
Cancer Res. 2008 Apr 1;68(7):2154-7
pubmed: 18381420
Cancers (Basel). 2020 May 05;12(5):
pubmed: 32380732
Breast Cancer Res Treat. 2017 Jun;163(2):383-390
pubmed: 28281021
Cancer Treat Rev. 2015 Jan;41(1):1-8
pubmed: 25467110
Cancer Med. 2019 Jun;8(6):2908-2918
pubmed: 31038845
J Natl Cancer Inst. 2016 Sep 06;109(1):
pubmed: 27601060
J Natl Compr Canc Netw. 2018 Nov;16(11):1362-1389
pubmed: 30442736
J Natl Cancer Inst. 1999 Aug 4;91(15):1310-6
pubmed: 10433620
Eur J Cancer. 2009 Nov;45(17):3000-7
pubmed: 19744851
Cancer Res Treat. 2020 Jul;52(3):697-713
pubmed: 32019277
ANZ J Surg. 2018 Oct;88(10):982-987
pubmed: 30141242
Biomed Res Int. 2013;2013:747318
pubmed: 23586058
Oncotarget. 2017 Jul 18;8(29):47064-47075
pubmed: 28423363
Eur J Cancer. 2019 Jan;106:54-60
pubmed: 30471648
Ann Oncol. 2019 Oct 1;30(10):1558-1571
pubmed: 31378807
J Clin Diagn Res. 2015 Sep;9(9):XC05-XC08
pubmed: 26500995
PLoS One. 2013 Jun 06;8(6):e62692
pubmed: 23762227
JAMA Oncol. 2015 Oct;1(7):943-51
pubmed: 26270727
J Clin Oncol. 2014 Jul 1;32(19):2001-9
pubmed: 24733792
Hum Mutat. 2008 Nov;29(11):1282-91
pubmed: 18951446
JAMA. 2017 Jun 20;317(23):2402-2416
pubmed: 28632866
Hum Mutat. 2016 Jun;37(6):564-9
pubmed: 26931183
J Clin Oncol. 2012 Dec 10;30(35):4308-16
pubmed: 23109706
Eur J Breast Health. 2020 Apr 01;16(2):129-136
pubmed: 32285035
J Clin Oncol. 2007 Sep 20;25(27):4210-6
pubmed: 17878475
N Engl J Med. 2015 Jun 4;372(23):2243-57
pubmed: 26014596
Cancer Discov. 2012 May;2(5):401-4
pubmed: 22588877
Nature. 1995 Dec 21-28;378(6559):789-92
pubmed: 8524414
Breast J. 2020 Jul;26(7):1337-1342
pubmed: 31999039
Breast Cancer Res. 2012 Apr 20;14(2):401
pubmed: 22520019
NPJ Breast Cancer. 2017 Jun 9;3:22
pubmed: 28649662
Br J Cancer. 2011 Apr 26;104(9):1384-92
pubmed: 21487411
Breast Cancer Res Treat. 2004 Jan;83(1):91-3
pubmed: 14997059
Sci Signal. 2013 Apr 02;6(269):pl1
pubmed: 23550210
Breast Cancer Res Treat. 2009 Jan;113(1):67-70
pubmed: 18228134
J Clin Oncol. 2009 Dec 10;27(35):5887-92
pubmed: 19858402
Science. 1994 Oct 7;266(5182):66-71
pubmed: 7545954
JAMA Surg. 2017 Jun 1;152(6):589-594
pubmed: 28423155
Nat Rev Clin Oncol. 2014 Mar;11(3):157-66
pubmed: 24492834
J Natl Cancer Inst. 2002 Sep 18;94(18):1358-65
pubmed: 12237281
Cancer. 2015 Jan 1;121(1):25-33
pubmed: 25186627
EPMA J. 2010 Sep;1(3):397-412
pubmed: 23199084

Auteurs

Daniele Fanale (D)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Lorena Incorvaia (L)

Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Clarissa Filorizzo (C)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Marco Bono (M)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Alessia Fiorino (A)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Valentina Calò (V)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Chiara Brando (C)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Lidia Rita Corsini (LR)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Nadia Barraco (N)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Giuseppe Badalamenti (G)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Antonio Russo (A)

Department of Surgical, Oncological and Oral Sciences, Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Viviana Bazan (V)

Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D.), Section of Medical Oncology, University of Palermo, 90127 Palermo, Italy.

Classifications MeSH