Impact of Red Yeast Rice on Metabolic Diseases: A Review of Possible Mechanisms of Action.


Journal

Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755

Informations de publication

Date de publication:
30 Sep 2020
Historique:
pubmed: 29 8 2020
medline: 7 2 2021
entrez: 29 8 2020
Statut: ppublish

Résumé

Metabolic diseases constitute a major public health burden and are linked with high morbidity and mortality. They comprise atherosclerosis dyslipidemia, diabetes, hypertension, and obesity. However, there is no single drug that can simultaneously treat multiple diseases with complex underlying mechanisms. Therefore, it is necessary to identify a class of adjuvant drugs that block the development of metabolic diseases from a preventive perspective. Red yeast rice is a food fermentation product widely used to promote blood circulation and remove blood stasis. Modern pharmacology has shown that red yeast rice exerts potential protective effects on the liver, pancreas, blood vessels, and intestines. Therefore, this study was carried out to analyze and summarize the effect of red yeast rice on several metabolic diseases and the mechanisms of action involved. It was found that red yeast rice may be beneficial in the prevention and treatment of metabolic diseases.

Identifiants

pubmed: 32854499
doi: 10.1021/acs.jafc.0c01893
doi:

Substances chimiques

Biological Products 0
red yeast rice 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

10441-10455

Auteurs

Ju Hu (J)

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People's Republic of China.

Jin Wang (J)

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People's Republic of China.

Qing-Xia Gan (QX)

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People's Republic of China.

Qian Ran (Q)

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People's Republic of China.

Guan-Hua Lou (GH)

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People's Republic of China.

Hai-Jun Xiong (HJ)

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People's Republic of China.

Cheng-Yi Peng (CY)

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People's Republic of China.

Ji-Lin Sun (JL)

Sichuan Fuzheng Pharmaceutical Company, Limited, Chengdu, Sichuan 610041, People's Republic of China.

Ren-Chuan Yao (RC)

Sichuan Fermentation Traditional Chinese Medicine Engineering Research Center, Chengdu, Sichuan 611130, People's Republic of China.

Qin-Wan Huang (QW)

College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, People's Republic of China.

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Classifications MeSH