Sex Cord Tumor With Annular Tubules-Like Histologic Pattern in Adult Granulosa Cell Tumor: Case Report of a Hitherto Unreported Morphologic Variant.
AGCT
FOXL2
SCTAT
adult granulosa cell tumor
sex cord tumor with annular tubules
Journal
International journal of surgical pathology
ISSN: 1940-2465
Titre abrégé: Int J Surg Pathol
Pays: United States
ID NLM: 9314927
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
pubmed:
29
8
2020
medline:
8
9
2021
entrez:
29
8
2020
Statut:
ppublish
Résumé
Adult granulosa cell tumor (AGCT) and sex cord tumor with annular tubules (SCTAT) are distinct sex cord stromal tumors with different molecular signatures. We present a unique case of an incidental ovarian tumor with mixed AGCT and SCTAT morphologic patterns. Due to the unusual co-occurrence, molecular testing was separately performed on both components. Despite minimal overlap in morphology, both the SCTAT and AGCT components were found to have an identical mutation profile, including the prototypical
Identifiants
pubmed: 32856501
doi: 10.1177/1066896920953620
doi:
Substances chimiques
FOXL2 protein, human
0
Forkhead Box Protein L2
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM