CYP19 gene rs2414096 variant and differential genetic risk of polycystic ovary syndrome: a systematic review and meta-analysis.

Aromatase / genetics Female Genetic Predisposition to Disease Humans Polycystic Ovary Syndrome / genetics
CYP19 polymorphism genetic risk Polycystic ovary syndrome (PCOS) meta-analysis steroidogenesis

Journal

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
ISSN: 1473-0766
Titre abrégé: Gynecol Endocrinol
Pays: England
ID NLM: 8807913

Informations de publication

Date de publication:
Feb 2021
Historique:
pubmed: 29 8 2020
medline: 30 10 2021
entrez: 29 8 2020
Statut: ppublish

Résumé

Previously, many studies investigated the association between CYP19 rs2414096(G > A) and susceptibility to develop PCOS. However, results had been inconsistent. Therefore, our systematic review and meta-analysis aimed to identify the association between CYP19 rs2414096 and PCOS risk.

Sections du résumé

BACKGROUND BACKGROUND
Previously, many studies investigated the association between CYP19 rs2414096(G > A) and susceptibility to develop PCOS. However, results had been inconsistent. Therefore, our systematic review and meta-analysis aimed to identify the association between CYP19 rs2414096 and PCOS risk.

Identifiants

DOI: 10.1080/09513590.2020.1813274 PMID: 32856958
pubmed: 32856958
doi: 10.1080/09513590.2020.1813274
doi:

Substances chimiques

Aromatase EC 1.14.14.1
CYP19A1 protein, human EC 1.14.14.1

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

126-131

Auteurs

Priya Sharma (P)

Department of Human Genetics and Molecular Medicine, School of Health Sciences, Central University of Punjab, Bathinda, India.

Mandeep Kaur (M)

Department of Human Genetics, Punjabi University, Patiala, India.

Preeti Khetarpal (P)

Department of Human Genetics and Molecular Medicine, School of Health Sciences, Central University of Punjab, Bathinda, India.
ORCID: 0000-0002-0510-3370

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochrome P-450 enzyme system › Steroid hydroxylases › Aromatase › CYP19 gene rs2414096 variant and differential...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › CYP19 gene rs2414096 variant and differential...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › CYP19 gene rs2414096 variant and differential...
questionsmedicales.fr › Maladies endocriniennes › Troubles gonadiques › Maladies ovariennes › Kystes de l'ovaire › Syndrome des ovaires polykystiques › CYP19 gene rs2414096 variant and differential...