Bacterial adhesion on orthopedic implants.
Bacterial adhesion
Biofilm
Coating
Infection
Orthopedic implants
Journal
Advances in colloid and interface science
ISSN: 1873-3727
Titre abrégé: Adv Colloid Interface Sci
Pays: Netherlands
ID NLM: 8706645
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
26
03
2020
revised:
29
07
2020
accepted:
30
07
2020
pubmed:
29
8
2020
medline:
29
6
2021
entrez:
29
8
2020
Statut:
ppublish
Résumé
Orthopedic implants are routinely used for fixation of fractures, correction of deformities, joint replacements, and soft tissue anchorage. Different biomaterials have been engineered for orthopedic implants. Previously, they were designed merely as mechanical devices, now new strategies to enhance bone healing and implant osteointegration via local delivery of molecules and via implant coatings are being developed. These biological coatings should enhance osteointegration and reduce foreign body response or infection. This article reviews current and future orthopedic implants, materials and surface characteristics, biocompatibility, and mechanisms of bacterial adhesion. Additionally, the review is addressing implant-related infection, the main strategies to prevent it and suggest possible future research that may control implant related-infection.
Identifiants
pubmed: 32858407
pii: S0001-8686(20)30200-1
doi: 10.1016/j.cis.2020.102228
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Coated Materials, Biocompatible
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
102228Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that there is no conflict of interest.