The association between serum omentin level and bodyweight: A systematic review and meta-analysis of observational studies.
Meta-analysis
Obesity
Omentin
Overweight
Systematic review
Journal
Clinical nutrition ESPEN
ISSN: 2405-4577
Titre abrégé: Clin Nutr ESPEN
Pays: England
ID NLM: 101654592
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
11
11
2019
revised:
19
05
2020
accepted:
14
06
2020
entrez:
30
8
2020
pubmed:
30
8
2020
medline:
25
9
2021
Statut:
ppublish
Résumé
A number of studies have examined the association between omentin and body weight, but the findings have been inconclusive. Here in, we systematically reviewed available observational studies to elucidate the overall relationship between omentin and body weight, by comparison of serum omentin level in overweight/obese and normal weight subjects. PubMed, Science direct, Scopus and ISI web of science databases were searched for all available literature until January 2020 for studies assessing the association between omentin and body weight. The Newcastle-Ottawa Quality Assessment Scale was used to assess the quality of each study. A total of 27 articles met the inclusion criteria and were included in our systematic review and meta-analysis. There was a significant association between omentin serum level and body weight (Standard Mean Difference (SMD) -0.43; 95% CI, -0.70 to -0.15; P = 0.002; I According to what was discussed, we found that serum omentin level is significantly lower in overweight subjects but not obese ones. This finding should be interpreted cautiously because of significant heterogeneity among included studies.
Sections du résumé
BACKGROUND AND AIMS
A number of studies have examined the association between omentin and body weight, but the findings have been inconclusive. Here in, we systematically reviewed available observational studies to elucidate the overall relationship between omentin and body weight, by comparison of serum omentin level in overweight/obese and normal weight subjects.
METHODS
PubMed, Science direct, Scopus and ISI web of science databases were searched for all available literature until January 2020 for studies assessing the association between omentin and body weight. The Newcastle-Ottawa Quality Assessment Scale was used to assess the quality of each study.
RESULTS
A total of 27 articles met the inclusion criteria and were included in our systematic review and meta-analysis. There was a significant association between omentin serum level and body weight (Standard Mean Difference (SMD) -0.43; 95% CI, -0.70 to -0.15; P = 0.002; I
CONCLUSION
According to what was discussed, we found that serum omentin level is significantly lower in overweight subjects but not obese ones. This finding should be interpreted cautiously because of significant heterogeneity among included studies.
Identifiants
pubmed: 32859320
pii: S2405-4577(20)30129-7
doi: 10.1016/j.clnesp.2020.06.014
pii:
doi:
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
22-29Informations de copyright
Copyright © 2020 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare no conflict of interest.