Investigation of pituitary adenylate cyclase activating polypeptide (PACAP) in human amniotic fluid samples.
Amniotic fluid
PACAP-like immunoreactivity
Pituitary adenylate cyclase activating polypeptide (PACAP)
Pregnancy
Journal
Reproductive biology
ISSN: 2300-732X
Titre abrégé: Reprod Biol
Pays: Poland
ID NLM: 101160559
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
09
03
2020
revised:
28
07
2020
accepted:
31
07
2020
pubmed:
30
8
2020
medline:
28
8
2021
entrez:
30
8
2020
Statut:
ppublish
Résumé
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide acting as a hormone, a neuromodulator, a neurotransmitter, a trophic factor and is involved in a variety of developmental and regenerative processes. PACAP is present in several human tissues and biological fluids. In many pathological conditions, changes in PACAP levels have been described to reflect disease progression, therefore PACAP has diagnostic value as a potential biomarker. Since PACAP has been shown to play an important role in reproductive physiology and development, it was of interest to examine whether this neuropeptide occurs in the human amniotic fluid. Amniotic fluid samples were collected between the 15-19
Identifiants
pubmed: 32859528
pii: S1642-431X(20)30254-0
doi: 10.1016/j.repbio.2020.07.013
pii:
doi:
Substances chimiques
Pituitary Adenylate Cyclase-Activating Polypeptide
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
491-495Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.