Functional respiratory imaging identifies redistribution of pulmonary blood flow in patients with COVID-19.


Journal

Thorax
ISSN: 1468-3296
Titre abrégé: Thorax
Pays: England
ID NLM: 0417353

Informations de publication

Date de publication:
02 2021
Historique:
received: 26 05 2020
revised: 27 07 2020
accepted: 12 08 2020
pubmed: 30 8 2020
medline: 6 7 2021
entrez: 30 8 2020
Statut: ppublish

Résumé

An increasing observation is that some patients with COVID-19 have normal lung compliance but significant hypoxaemia different from typical acute respiratory distress syndrome (ARDS). We hypothesised that changes in pulmonary blood distribution may be partially responsible and used functional respiratory imaging on CT scans to calculate pulmonary blood volume. We found that patients with COVID-19 had significantly reduced blood volume in the smaller calibre blood vessels (here defined as <5 mm

Identifiants

pubmed: 32859733
pii: thoraxjnl-2020-215395
doi: 10.1136/thoraxjnl-2020-215395
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

182-184

Commentaires et corrections

Type : CommentIn

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: JDB, MLL and WD are employees of Fluidda NV who performed the functional respiratory imaging analysis. MT and AR are directors of Qureight who performed the data analytics.

Auteurs

Muhunthan Thillai (M)

Royal Papworth Hospital, Cambridge, UK muhunthan.thillai@nhs.net.
Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.

Chinmay Patvardhan (C)

Royal Papworth Hospital, Cambridge, UK.

Emilia M Swietlik (EM)

Royal Papworth Hospital, Cambridge, UK.
Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.

Tom McLellan (T)

Royal Papworth Hospital, Cambridge, UK.

Jan De Backer (J)

Fluidda NV, Antwerp, Belgium.

Maarten Lanclus (M)

Fluidda NV, Antwerp, Belgium.

Wilfried De Backer (W)

Fluidda NV, Antwerp, Belgium.

Alessandro Ruggiero (A)

Royal Papworth Hospital, Cambridge, UK.

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Classifications MeSH