MerTK Expression and ERK Activation Are Essential for the Functional Maturation of Osteopontin-Producing Reparative Macrophages After Myocardial Infarction.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
15 09 2020
Historique:
pubmed: 1 9 2020
medline: 12 3 2021
entrez: 1 9 2020
Statut: ppublish

Résumé

Background We previously reported that osteopontin plays an essential role in accelerating both reparative fibrosis and clearance of dead cells (efferocytosis) during tissue repair after myocardial infarction (MI) and galectin-3

Identifiants

pubmed: 32865099
doi: 10.1161/JAHA.120.017071
pmc: PMC7726992
doi:

Substances chimiques

STAT3 Transcription Factor 0
Spp1 protein, mouse 0
Stat3 protein, mouse 0
Osteopontin 106441-73-0
Mertk protein, mouse EC 2.7.10.1
c-Mer Tyrosine Kinase EC 2.7.10.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e017071

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Auteurs

Kohsuke Shirakawa (K)

Department of Cardiovascular Biology and Medicine Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.
Department of Cardiology Keio University School of Medicine Tokyo Japan.

Jin Endo (J)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Masaharu Kataoka (M)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Yoshinori Katsumata (Y)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Atsushi Anzai (A)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Hidenori Moriyama (H)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Hiroki Kitakata (H)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Takahiro Hiraide (T)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Seien Ko (S)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Shinichi Goto (S)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Genki Ichihara (G)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Keiichi Fukuda (K)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

Tohru Minamino (T)

Department of Cardiovascular Biology and Medicine Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.

Motoaki Sano (M)

Department of Cardiology Keio University School of Medicine Tokyo Japan.

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Classifications MeSH