Chloroquine combined with concurrent radiotherapy and temozolomide for newly diagnosed glioblastoma: a phase IB trial.
Autophagy
brain tumor
chloroquine
glioblastoma
radiotherapy
temozolomide
Journal
Autophagy
ISSN: 1554-8635
Titre abrégé: Autophagy
Pays: United States
ID NLM: 101265188
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
pubmed:
1
9
2020
medline:
8
4
2022
entrez:
1
9
2020
Statut:
ppublish
Résumé
Treatment of glioblastoma xenografts with chloroquine results in macroautophagy/autophagy inhibition, resulting in a reduction of tumor hypoxia and sensitization to radiation. Preclinical data show that
Identifiants
pubmed: 32866424
doi: 10.1080/15548627.2020.1816343
pmc: PMC8496728
doi:
Substances chimiques
Chloroquine
886U3H6UFF
Temozolomide
YF1K15M17Y
Types de publication
Clinical Trial, Phase I
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2604-2612Références
Autophagy. 2014 Aug;10(8):1359-68
pubmed: 24991840
J Natl Cancer Inst. 2009 May 20;101(10):708-20
pubmed: 19436029
Radiother Oncol. 2009 Sep;92(3):399-404
pubmed: 19616331
Oncol Lett. 2017 Jul;14(1):322-328
pubmed: 28693171
Cancer Chemother Pharmacol. 2017 Nov;80(5):1005-1012
pubmed: 28980060
Cancer Lett. 2015 May 1;360(2):195-204
pubmed: 25681668
Radiother Oncol. 2009 Sep;92(3):411-6
pubmed: 19616335
Front Oncol. 2018 Aug 27;8:335
pubmed: 30211116
J Clin Invest. 2010 Jan;120(1):127-41
pubmed: 20038797
Cell. 2013 Oct 10;155(2):462-77
pubmed: 24120142
Eur J Pharmacol. 2016 Jan 15;771:139-44
pubmed: 26687632
Autophagy. 2018;14(2):283-295
pubmed: 29377763
Ann Intern Med. 2006 Mar 7;144(5):337-43
pubmed: 16520474
EMBO J. 2006 Feb 22;25(4):683-92
pubmed: 16467847
Neuro Oncol. 2015 Jun;17(6):776-83
pubmed: 25313193
Cancer Lett. 2015 Mar 28;358(2):220-231
pubmed: 25542083
PLoS One. 2012;7(6):e38706
pubmed: 22745676
J Neurosurg. 2003 Feb;98(2):378-84
pubmed: 12593626
Breast Cancer Res Treat. 2019 Nov;178(2):327-335
pubmed: 31392517
Cell Death Differ. 2005 Nov;12 Suppl 2:1535-41
pubmed: 16247501
Lancet Infect Dis. 2007 Aug;7(8):549-58
pubmed: 17646028
Neuro Oncol. 2014 Oct;16 Suppl 8:viii1-6
pubmed: 25342599
Lancet Oncol. 2009 May;10(5):459-66
pubmed: 19269895
Cancer Res. 2001 Jan 15;61(2):439-44
pubmed: 11212227
Science. 2014 Jun 20;344(6190):1396-401
pubmed: 24925914
J Pharm Pharmacol. 1982 Nov;34(11):733-5
pubmed: 6129306
BMC Neurol. 2016 Sep 20;16(1):178
pubmed: 27644442
Autophagy. 2012 Feb 1;8(2):200-12
pubmed: 22252008
Anticancer Drugs. 2013 Jan;24(1):14-9
pubmed: 23111416
Lancet Oncol. 2017 Jun;18(6):e315-e329
pubmed: 28483413
Strahlenther Onkol. 2014 Oct;190(10):957-61
pubmed: 24928248
Neurosurg Focus. 2014 Dec;37(6):E12
pubmed: 25434381
Ophthalmology. 2011 Feb;118(2):415-22
pubmed: 21292109
Cell Death Differ. 2004 Apr;11(4):448-57
pubmed: 14713959
Nat Med. 2007 Sep;13(9):1050-9
pubmed: 17704786
Cell Death Differ. 2014 Jan;21(1):92-9
pubmed: 24037090
Int J Oncol. 2005 May;26(5):1401-10
pubmed: 15809734
Cancer Biol Ther. 2009 Apr;8(8):730-8
pubmed: 19252415
Mol Biol Cell. 2004 Mar;15(3):1101-11
pubmed: 14699058
Ther Drug Monit. 1989;11(4):369-79
pubmed: 2662478
PLoS One. 2012;7(10):e47357
pubmed: 23091617
Cancer Res. 2003 Oct 15;63(20):6962-70
pubmed: 14583498
Cancer Cell. 2014 Aug 11;26(2):190-206
pubmed: 25117709
Oncoimmunology. 2014 Jul 03;3(7):e944047
pubmed: 25610726
Surg Neurol. 2007 Apr;67(4):388-91
pubmed: 17350410
Cell Death Dis. 2013 Oct 10;4:e838
pubmed: 24113172
J Neurooncol. 2015 Mar;122(1):11-20
pubmed: 25528635
Eur J Clin Pharmacol. 1992;42(4):429-33
pubmed: 1307690
Radiother Oncol. 2007 Jun;83(3):333-9
pubmed: 17512071
Drug Resist Updat. 2004 Feb;7(1):25-40
pubmed: 15072769
Lancet Infect Dis. 2003 Nov;3(11):722-7
pubmed: 14592603
Acta Neuropathol. 2016 Jun;131(6):803-20
pubmed: 27157931