Photoperiod-induced changes in hypothalamic de novo DNA methyltransferase expression are independent of triiodothyronine in female Siberian hamsters (Phodopus sungorus).
Hamster
Rhythmic epigenetics
Seasonal
Sex differences
Triiodothyronine
Journal
General and comparative endocrinology
ISSN: 1095-6840
Titre abrégé: Gen Comp Endocrinol
Pays: United States
ID NLM: 0370735
Informations de publication
Date de publication:
01 12 2020
01 12 2020
Historique:
received:
15
04
2020
revised:
17
08
2020
accepted:
24
08
2020
pubmed:
1
9
2020
medline:
20
4
2021
entrez:
1
9
2020
Statut:
ppublish
Résumé
Many temperate zone animals engage in seasonal reproductive physiology and behavior as a strategy to maximise the propagation of the species. The hypothalamus integrates environmental cues and hormonal signalling to optimize the timing of reproduction. Recent work has revealed that epigenetic modifications, such as DNA methylation, vary across seasonal reproductive states. Multiple hormones act in the hypothalamus to permit or inhibit reproductive physiology, and the increase in thyroid hormone triiodothyronine (T
Identifiants
pubmed: 32866475
pii: S0016-6480(20)30357-9
doi: 10.1016/j.ygcen.2020.113604
pii:
doi:
Substances chimiques
Triiodothyronine
06LU7C9H1V
Methyltransferases
EC 2.1.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
113604Informations de copyright
Crown Copyright © 2020. Published by Elsevier Inc. All rights reserved.