Vascular Calcifications are Associated with Increased Mortality in Patients with Acute Mesenteric Ischemia.


Journal

Annals of vascular surgery
ISSN: 1615-5947
Titre abrégé: Ann Vasc Surg
Pays: Netherlands
ID NLM: 8703941

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 22 05 2020
revised: 07 08 2020
accepted: 10 08 2020
pubmed: 1 9 2020
medline: 3 8 2021
entrez: 1 9 2020
Statut: ppublish

Résumé

Vascular calcifications have been identified as predictors of mortality in several cardiovascular diseases but have not been investigated in context of acute mesenteric ischemia. The aim of this study was to investigate the impact of vascular calcifications in patients with acute mesenteric ischemia. Patients admitted for an acute mesenteric ischemia were retrospectively included. The presence of calcifications in the visceral aorta, the celiac trunk, the superior mesenteric artery, and the renal arteries was assessed on computed tomography scan images at the arterial phase. The calcification volumes were measured using the software Aquarius iNtuition Edition®. The all-cause mortality was 55 out of 86 patients (63.9%) for a median follow-up of 3.5 days (1-243). The survival rate of patients with calcification in the superior mesenteric artery was significantly lower than that of those without calcification (22% vs. 55.6%, P = 0.019). Patients who died had significantly a higher frequency of calcifications in the superior mesenteric artery, the visceral aorta, the celiac trunk, and the renal arteries. The presence of vascular calcifications in the superior mesenteric artery is associated with increased mortality in patients diagnosed with acute mesenteric ischemia. Further studies are required to identify the mechanisms underlying this association.

Sections du résumé

BACKGROUND BACKGROUND
Vascular calcifications have been identified as predictors of mortality in several cardiovascular diseases but have not been investigated in context of acute mesenteric ischemia. The aim of this study was to investigate the impact of vascular calcifications in patients with acute mesenteric ischemia.
METHODS METHODS
Patients admitted for an acute mesenteric ischemia were retrospectively included. The presence of calcifications in the visceral aorta, the celiac trunk, the superior mesenteric artery, and the renal arteries was assessed on computed tomography scan images at the arterial phase. The calcification volumes were measured using the software Aquarius iNtuition Edition®.
RESULTS RESULTS
The all-cause mortality was 55 out of 86 patients (63.9%) for a median follow-up of 3.5 days (1-243). The survival rate of patients with calcification in the superior mesenteric artery was significantly lower than that of those without calcification (22% vs. 55.6%, P = 0.019). Patients who died had significantly a higher frequency of calcifications in the superior mesenteric artery, the visceral aorta, the celiac trunk, and the renal arteries.
CONCLUSIONS CONCLUSIONS
The presence of vascular calcifications in the superior mesenteric artery is associated with increased mortality in patients diagnosed with acute mesenteric ischemia. Further studies are required to identify the mechanisms underlying this association.

Identifiants

pubmed: 32866577
pii: S0890-5096(20)30766-4
doi: 10.1016/j.avsg.2020.08.086
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

88-97

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Fabien Lareyre (F)

Department of Vascular Surgery, University Hospital of Nice, France; Université Côte d'Azur, CHU, Inserm U1065, C3M, Nice, France. Electronic address: fabien.lareyre@gmail.com.

Emmanuel Augène (E)

Department of Visceral Surgery, University Hospital of Nice, France.

Damien Massalou (D)

Department of Visceral Surgery, University Hospital of Nice, France.

Julien Chikande (J)

Department of Vascular Surgery, University Hospital of Nice, France.

Lucas Guidi (L)

Department of Vascular Surgery, University Hospital of Nice, France.

Elixène Jean-Baptiste (E)

Department of Vascular Surgery, University Hospital of Nice, France; Université Côte d'Azur, CHU, Inserm U1065, C3M, Nice, France.

Réda Hassen-Khodja (R)

Department of Vascular Surgery, University Hospital of Nice, France; Université Côte d'Azur, CHU, Inserm U1065, C3M, Nice, France.

Juliette Raffort (J)

Université Côte d'Azur, CHU, Inserm U1065, C3M, Nice, France; Clinical Chemistry Laboratory, Department of Clinical Biochemistry, University Hospital of Nice, France.

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Classifications MeSH