The SNM1A DNA repair nuclease.
DCLRE1A
Interstrand crosslink repair
Nuclease
Pso2
SNM1A
Journal
DNA repair
ISSN: 1568-7856
Titre abrégé: DNA Repair (Amst)
Pays: Netherlands
ID NLM: 101139138
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
25
07
2020
accepted:
25
07
2020
pubmed:
1
9
2020
medline:
1
4
2021
entrez:
1
9
2020
Statut:
ppublish
Résumé
Unrepaired, or misrepaired, DNA damage can contribute to the pathogenesis of a number of conditions, or disease states; thus, DNA damage repair pathways, and the proteins within them, are required for the safeguarding of the genome. Human SNM1A is a 5'-to-3' exonuclease that plays a role in multiple DNA damage repair processes. To date, most data suggest a role of SNM1A in primarily ICL repair: SNM1A deficient cells exhibit hypersensitivity to ICL-inducing agents (e.g. mitomycin C and cisplatin); and both in vivo and in vitro experiments demonstrate SNM1A and XPF-ERCC1 can function together in the 'unhooking' step of ICL repair. SNM1A further interacts with a number of other proteins that contribute to genome integrity outside canonical ICL repair (e.g. PCNA and CSB), and these may play a role in regulating SNM1As function, subcellular localisation, and post-translational modification state. These data also provide further insight into other DNA repair pathways to which SNM1A may contribute. This review aims to discuss all aspects of the exonuclease, SNM1A, and its contribution to DNA damage tolerance.
Identifiants
pubmed: 32866775
pii: S1568-7864(20)30190-7
doi: 10.1016/j.dnarep.2020.102941
pmc: PMC7607226
pii:
doi:
Substances chimiques
Cell Cycle Proteins
0
DNA Adducts
0
DNA
9007-49-2
DCLRE1A protein, human
EC 3.1.-
Exodeoxyribonucleases
EC 3.1.-
DNA Repair Enzymes
EC 6.5.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
102941Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/L007665/1
Pays : United Kingdom
Organisme : Cancer Research UK
ID : A24759
Pays : United Kingdom
Informations de copyright
Crown Copyright © 2020. Published by Elsevier B.V. All rights reserved.
Références
FEBS Lett. 2001 Aug 10;503(1):1-6
pubmed: 11513844
J Biol Chem. 2009 Oct 9;284(41):27908-17
pubmed: 19684342
Cell Mol Life Sci. 2016 Aug;73(16):3097-114
pubmed: 27094386
Science. 2019 Feb 15;363(6428):
pubmed: 30765538
Mol Genet Metab. 2008 May;94(1):38-45
pubmed: 18180189
Mol Cell Biol. 2000 Jul;20(13):4553-61
pubmed: 10848582
Nature. 2006 Dec 14;444(7121):953-6
pubmed: 17128255
Eur J Cancer. 2018 Oct;102:31-39
pubmed: 30114658
DNA Repair (Amst). 2002 May 30;1(5):379-90
pubmed: 12509242
Mech Ageing Dev. 2013 May-Jun;134(5-6):202-11
pubmed: 23422418
J Cell Biol. 2000 Dec 25;151(7):1381-90
pubmed: 11134068
Mol Cell Proteomics. 2014 Feb;13(2):397-406
pubmed: 24309898
Science. 2009 Dec 18;326(5960):1698-701
pubmed: 19965384
Mol Gen Genet. 1981;181(3):346-51
pubmed: 7017347
J Bacteriol. 1981 Oct;148(1):248-56
pubmed: 7026532
Cell. 2016 Oct 6;167(2):498-511.e14
pubmed: 27693351
PLoS Genet. 2018 Jul 30;14(7):e1007541
pubmed: 30059501
J Ovarian Res. 2016 Nov 2;9(1):73
pubmed: 27806724
DNA Repair (Amst). 2005 Feb 3;4(2):163-70
pubmed: 15590324
Mol Cell Biol. 2005 Nov;25(22):10071-8
pubmed: 16260620
Mol Cell Biol. 2004 Dec;24(24):10733-41
pubmed: 15572677
Nucleic Acids Res. 2012 Mar;40(5):2131-9
pubmed: 22102580
Biochem Biophys Res Commun. 2008 Dec 5;377(1):236-41
pubmed: 18848520
Mol Cell. 2013 Nov 7;52(3):434-46
pubmed: 24207054
Genes Dev. 2016 Mar 15;30(6):645-59
pubmed: 26980189
Genes Dev. 2011 Sep 1;25(17):1859-70
pubmed: 21896658
Biochem Biophys Res Commun. 2011 Jul 8;410(3):568-73
pubmed: 21683065
Structure. 2011 Sep 7;19(9):1252-61
pubmed: 21893286
Mol Cell. 2014 Oct 2;56(1):174-85
pubmed: 25219499
Nucleic Acids Res. 2012 Oct;40(18):8953-64
pubmed: 22810206
Curr Biol. 2006 Jul 11;16(13):1303-10
pubmed: 16730175
Nat Struct Mol Biol. 2015 Mar;22(3):242-7
pubmed: 25643322
Trends Biochem Sci. 2013 Aug;38(8):386-93
pubmed: 23830640
Cell. 2005 Dec 29;123(7):1191-8
pubmed: 16377561
Mol Cell Biol. 1997 Oct;17(10):6087-96
pubmed: 9315668
DNA Res. 1995;2(1):37-43
pubmed: 7788527
DNA Repair (Amst). 2008 Feb 1;7(2):230-8
pubmed: 18006388
J Biol Chem. 2015 Sep 11;290(37):22602-11
pubmed: 26221031
J Inorg Biochem. 2016 Oct;163:185-193
pubmed: 27498591
J Biol Chem. 2009 Jul 3;284(27):18236-43
pubmed: 19423708
Mutat Res. 2003 Nov;544(2-3):179-93
pubmed: 14644320
Nucleic Acids Res. 2015 Jan;43(1):247-58
pubmed: 25505141
Mol Cell. 2015 Sep 17;59(6):998-1010
pubmed: 26365379
Mol Cell Biol. 2003 Jan;23(2):754-61
pubmed: 12509472
Cell. 2001 Apr 20;105(2):177-86
pubmed: 11336668
Mol Cell. 2002 Dec;10(6):1379-90
pubmed: 12504013
Nucleic Acids Res. 2015 Dec 15;43(22):11047-60
pubmed: 26582912
Science. 2014 Nov 28;346(6213):1127-30
pubmed: 25430771
Cold Spring Harb Perspect Biol. 2013 Oct 01;5(10):a012732
pubmed: 24086043
Chromosoma. 2014 Mar;123(1-2):79-90
pubmed: 24162931
Mol Cell Biol. 2002 Dec;22(24):8635-47
pubmed: 12446782
Nat Commun. 2018 Jul 3;9(1):2592
pubmed: 29968717
Cell. 2002 Mar 22;108(6):781-94
pubmed: 11955432
Science. 2019 Sep 6;365(6457):
pubmed: 31395743
Cell. 2011 Sep 16;146(6):931-41
pubmed: 21925316
Hum Mol Genet. 2011 Jul 1;20(13):2549-59
pubmed: 21478198
Hum Mol Genet. 2012 Nov 15;21(22):4948-56
pubmed: 22907656
Oncogene. 2008 Aug 28;27(37):5045-56
pubmed: 18469862
EMBO J. 2009 Dec 2;28(23):3657-66
pubmed: 19851286
Mol Cell Biol. 2007 Apr;27(7):2625-35
pubmed: 17242184
Genetics. 1980 Jun;95(2):273-88
pubmed: 7009316
Org Biomol Chem. 2019 Sep 21;17(35):8094-8105
pubmed: 31380542
Nat Rev Cancer. 2008 Mar;8(3):193-204
pubmed: 18256616
DNA Repair (Amst). 2014 Jul;19:135-42
pubmed: 24768452
J Biol Chem. 2010 Jun 18;285(25):19085-91
pubmed: 20385554
Ann N Y Acad Sci. 2013 Jan;1277:91-104
pubmed: 23163348
Nature. 2019 Mar;567(7747):267-272
pubmed: 30842657
Curr Biol. 2006 Jul 11;16(13):1295-302
pubmed: 16730176
Nat Rev Gastroenterol Hepatol. 2020 Jun;17(6):317-318
pubmed: 32317778
Mol Cell Biol. 2004 Dec;24(23):10448-55
pubmed: 15542852
Nat Cell Biol. 2014 Mar;16(3):281-93
pubmed: 24561620
Chem Commun (Camb). 2016 May 10;52(40):6727-30
pubmed: 27121860
J Surg Oncol. 2020 Apr;121(5):906-916
pubmed: 31650563
Cell Rep. 2018 Jun 19;23(12):3419-3428
pubmed: 29924986
Mol Cell. 2015 Nov 19;60(4):547-60
pubmed: 26590714
Nature. 2008 Jan 3;451(7174):81-5
pubmed: 18172500
Nucleic Acids Res. 2020 Apr 6;48(6):3014-3028
pubmed: 31980815
Nucleic Acids Res. 2002 Jan 1;30(1):166-8
pubmed: 11752282
Oncogene. 2004 Nov 11;23(53):8611-8
pubmed: 15467758
DNA Repair (Amst). 2008 Aug 2;7(8):1192-201
pubmed: 18468965
Mol Cell Biol. 2001 Mar;21(5):1719-29
pubmed: 11238909
J Biol Chem. 2006 Jun 2;281(22):15033-6
pubmed: 16606622
Nucleic Acids Res. 2007;35(18):6115-23
pubmed: 17804464
Science. 2011 Jul 1;333(6038):84-7
pubmed: 21719678
Mutat Res. 1981 Nov;91(6):457-62
pubmed: 7027037
Curr Genet. 1988;13(1):37-40
pubmed: 3282695
Cell Rep. 2019 May 7;27(6):1794-1808.e5
pubmed: 31067464
Nat Commun. 2014 Dec 11;5:5726
pubmed: 25500724
Nat Rev Cancer. 2011 Jun 24;11(7):467-80
pubmed: 21701511
Nucleic Acids Res. 2002 Aug 15;30(16):3592-601
pubmed: 12177301
Nucleic Acids Res. 2018 Sep 28;46(17):9057-9066
pubmed: 30165656
J Biol Chem. 2012 Jul 27;287(31):26254-67
pubmed: 22692201
Mol Gen Genet. 1996 Feb 5;250(2):162-8
pubmed: 8628215
DNA Repair (Amst). 2005 May 2;4(5):556-70
pubmed: 15811628
J Cell Biol. 2010 Oct 18;191(2):249-57
pubmed: 20937699
Mutat Res. 1998 Oct 21;409(1):11-6
pubmed: 9806498
Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):2298-302
pubmed: 7892263
DNA Repair (Amst). 2005 Jul 12;4(7):845-51
pubmed: 15936993
Annu Rev Cancer Biol. 2019 Mar;3:457-478
pubmed: 30882047
J Biol Chem. 2006 Sep 22;281(38):27784-93
pubmed: 16857680
Nat Rev Mol Cell Biol. 2011 Feb;12(2):90-103
pubmed: 21252998
Nat Struct Mol Biol. 2008 Feb;15(2):206-12
pubmed: 18204464
Antimicrob Agents Chemother. 2004 Jul;48(7):2347-9
pubmed: 15215079
Nat Rev Mol Cell Biol. 2001 Mar;2(3):202-10
pubmed: 11265250
EMBO J. 2017 Jul 14;36(14):2047-2060
pubmed: 28607004
Science. 2015 May 1;348(6234):1253671
pubmed: 25931565
Nucleic Acids Res. 2005 Sep 25;33(17):5382-93
pubmed: 16186129
Cell. 2008 Sep 19;134(6):969-80
pubmed: 18805090
Carcinogenesis. 2006 Dec;27(12):2448-54
pubmed: 16774934
PLoS Genet. 2020 Apr 9;16(4):e1008616
pubmed: 32271747
Biochem Pharmacol. 2007 Dec 15;74(12):1686-701
pubmed: 17597585
Structure. 2011 Sep 7;19(9):1241-51
pubmed: 21893285
J Biol Chem. 2018 Jul 6;293(27):10512-10523
pubmed: 29247009
In Silico Biol. 1999;1(2):69-91
pubmed: 11471246
BMC Cancer. 2019 Apr 4;19(1):313
pubmed: 30947698
Mol Cell. 2014 May 8;54(3):460-71
pubmed: 24726325