Differences in Gut Microbiome Composition between Senior Orienteering Athletes and Community-Dwelling Older Adults.
Faecalibacterium prausnitzii
aged
gut microbiota
metagenomics
orienteering
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
27 Aug 2020
27 Aug 2020
Historique:
received:
18
07
2020
revised:
14
08
2020
accepted:
18
08
2020
entrez:
2
9
2020
pubmed:
2
9
2020
medline:
30
3
2021
Statut:
epublish
Résumé
Gastrointestinal (GI) health is an important aspect of general health. Gastrointestinal symptoms are of specific importance for the elderly, an increasing group globally. Hence, promoting the elderly's health and especially gastrointestinal health is important. Gut microbiota can influence gastrointestinal health by modulation of the immune system and the gut-brain axis. Diverse gut microbiota have been shown to be beneficial; however, for the elderly, the gut microbiota is often less diverse. Nutrition and physical activity, in particular, are two components that have been suggested to influence composition or diversity. In this study, we compared gut microbiota between two groups of elderly individuals: community-dwelling older adults and physically active senior orienteering athletes, where the latter group has less gastrointestinal symptoms and a reported better well-being. With this approach, we explored if certain gut microbiota were related to healthy ageing. The participant data and faecal samples were collected from these two groups and the microbiota was whole-genome sequenced and taxonomically classified with MetaPhlAn. The physically active senior orienteers had a more homogeneous microbiota within the group and a higher abundance of Our results suggest specific composition characteristics of healthy microbiota in the elderly, and show that certain components of nutrition as well as psychological distress are not as tightly connected with composition or diversity variation in faecal microbiota samples.
Sections du résumé
BACKGROUND
BACKGROUND
Gastrointestinal (GI) health is an important aspect of general health. Gastrointestinal symptoms are of specific importance for the elderly, an increasing group globally. Hence, promoting the elderly's health and especially gastrointestinal health is important. Gut microbiota can influence gastrointestinal health by modulation of the immune system and the gut-brain axis. Diverse gut microbiota have been shown to be beneficial; however, for the elderly, the gut microbiota is often less diverse. Nutrition and physical activity, in particular, are two components that have been suggested to influence composition or diversity.
MATERIALS AND METHODS
METHODS
In this study, we compared gut microbiota between two groups of elderly individuals: community-dwelling older adults and physically active senior orienteering athletes, where the latter group has less gastrointestinal symptoms and a reported better well-being. With this approach, we explored if certain gut microbiota were related to healthy ageing. The participant data and faecal samples were collected from these two groups and the microbiota was whole-genome sequenced and taxonomically classified with MetaPhlAn.
RESULTS
RESULTS
The physically active senior orienteers had a more homogeneous microbiota within the group and a higher abundance of
CONCLUSIONS
CONCLUSIONS
Our results suggest specific composition characteristics of healthy microbiota in the elderly, and show that certain components of nutrition as well as psychological distress are not as tightly connected with composition or diversity variation in faecal microbiota samples.
Identifiants
pubmed: 32867153
pii: nu12092610
doi: 10.3390/nu12092610
pmc: PMC7551621
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Bo Rydins Stiftelse för Vetenskaplig Forskning
ID : F0514
Organisme : Stiftelsen för Kunskaps- och Kompetensutveckling
ID : 20110225
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