Prevalence of Antibodies to SARS-CoV-2 in Italian Adults and Associated Risk Factors.

COVID-19 SARS-CoV-2 antibodies serological test

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
27 Aug 2020
Historique:
received: 29 06 2020
revised: 08 08 2020
accepted: 18 08 2020
entrez: 2 9 2020
pubmed: 2 9 2020
medline: 2 9 2020
Statut: epublish

Résumé

We aimed to assess the prevalence of and factors associated with anti- severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) positivity in a large population of adult volunteers from five administrative departments of the Liguria and Lombardia regions. A total of 3609 individuals were included in this analysis. Participants were tested for anti-SARS-CoV-2 antibodies [Immunoglobulin G (IgG) and M (IgM) class antibodies] at three private laboratories (Istituto Diganostico Varelli, Medical Center, and Casa della Salute di Genova). Demographic data, occupational or private exposure to SARS-CoV-2-infected patients, and prior medical history consistent with SARS-CoV-2 infection were collected according to a preplanned analysis. The overall seroprevalence of anti-SARS-CoV-2 antibodies (IgG and/or IgM) was 11.0% [398/3609; confidence interval (CI) 10.0%-12.1%]. Seroprevalence was higher in female inmates than in male inmates (12.5% vs. 9.2%, respectively,

Identifiants

pubmed: 32867328
pii: jcm9092780
doi: 10.3390/jcm9092780
pmc: PMC7563864
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Clin Microbiol Infect. 2020 Jul;26(7):948.e1-948.e3
pubmed: 32360780
Emerg Infect Dis. 2020 Nov;26(11):2761-2763
pubmed: 32726200
Clin Chem Lab Med. 2020 Jun 25;58(7):1156-1159
pubmed: 32301750
Lancet. 2020 Aug 1;396(10247):313-319
pubmed: 32534626
Crit Rev Clin Lab Sci. 2020 Sep;57(6):400-414
pubmed: 32662342
J Clin Virol. 2003 Jul;27(2):170-9
pubmed: 12829039
Travel Med Infect Dis. 2020 May - Jun;35:101608
pubmed: 32114075
J Med Virol. 2020 May 8;:
pubmed: 32383174
BMJ. 2020 May 4;369:m1818
pubmed: 32366498
Clin Geriatr Med. 2016 Aug;32(3):585-607
pubmed: 27394025
J Med Virol. 2020 Feb 27;:
pubmed: 32104917
Diagnostics (Basel). 2020 Jul 04;10(7):
pubmed: 32635444
BMC Infect Dis. 2016 Nov 4;16(1):637
pubmed: 27814689
MMWR Morb Mortal Wkly Rep. 2020 Jul 24;69(29):965-970
pubmed: 32701941
Lancet. 2020 Aug 22;396(10250):535-544
pubmed: 32645347
Euro Surveill. 2020 Mar;25(10):
pubmed: 32183930
ACS Chem Neurosci. 2020 May 6;11(9):1200-1203
pubmed: 32283006
MMWR Morb Mortal Wkly Rep. 2020 Jul 24;69(29):960-964
pubmed: 32701938
JAMA. 2020 Jun 16;323(23):2425-2427
pubmed: 32421144
Eur J Clin Invest. 2020 Mar;50(3):e13209
pubmed: 32003000
J Am Med Dir Assoc. 2016 Jan;17(1):85-8
pubmed: 26712489
JAMA Intern Med. 2020 Jul 21;:
pubmed: 32692365
Clin Infect Dis. 2020 Jun 16;:
pubmed: 32544951
N Engl J Med. 2020 May 21;382(21):2005-2011
pubmed: 32220208
J Am Geriatr Soc. 2020 Aug;68(8):1653-1656
pubmed: 32484912
Euro Surveill. 2020 Jun;25(24):
pubmed: 32583766
Emerg Infect Dis. 2019 Feb;25(2):383-384
pubmed: 30666949
Euro Surveill. 2020 Jul;25(28):
pubmed: 32700672
Clin Chem Lab Med. 2020 Jun 25;58(7):1081-1088
pubmed: 32301749
J Am Geriatr Soc. 2020 May;68(5):942
pubmed: 32216132
JAMA. 2020 May 12;323(18):1775-1776
pubmed: 32203977
J Am Med Dir Assoc. 2020 Jan;21(1):104-109.e1
pubmed: 31101588
Geriatr Nurs. 2015 Jul-Aug;36(4):267-72
pubmed: 25794923
Rev Saude Publica. 2020;54:69
pubmed: 32638883

Auteurs

Antonio Vena (A)

Infectious Diseases Unit, San Martino Policlinico Hospital-IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Marco Berruti (M)

Infectious Diseases Unit, San Martino Policlinico Hospital-IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, 16132 Genoa, Italy.

Andrea Adessi (A)

Onilab Milano, 20123 Milano, Italy.

Pietro Blumetti (P)

Medical Center srl, Sesto Calende, 21018 Varese, Italy.

Michele Brignole (M)

Department of Cardiology, Arrhytmology Centre and Syncope Unit, Ospedale del Tigullio, 16033 Lavagna, Italy.
IRCCS Istituto Auxologico Italiano, Faint and Fall Programme, Ospedale San Luca, 20149 Milano, Italy.

Renato Colognato (R)

Medical Center srl, Sesto Calende, 21018 Varese, Italy.

Germano Gaggioli (G)

Division of Cardiology, Ospedale Villa Scassi, 16149 Genova, Italy.

Daniele Roberto Giacobbe (DR)

Infectious Diseases Unit, San Martino Policlinico Hospital-IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Luisa Bracci-Laudiero (L)

Institute of Translational Pharmacology, Consiglio Nazionale Delle Ricerche (CNR), 00185 Rome, Italy.
Division of Rheumatology and Immuno-Rheumatology Research Laboratories, Bambino Gesù Children's Hospital, 00165 Rome, Italy.

Laura Magnasco (L)

Infectious Diseases Unit, San Martino Policlinico Hospital-IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Alessio Signori (A)

Section of Biostatistics, Department of Health Sciences, University of Genova, 16132 Genova, Italy.

Lucia Taramasso (L)

Infectious Diseases Unit, San Martino Policlinico Hospital-IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Marco Varelli (M)

Diagnostic Institute Varelli, Clinical Analysis, 80126 Napoli, Italy.

Nicoletta Vendola (N)

Division of Obstetrics and Gynecology, Sant'Andrea Hospital, 13100 Vercelli, Italy.

Lorenzo Ball (L)

Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132 Genoa, Italy.
Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Chiara Robba (C)

Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Denise Battaglini (D)

Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Iole Brunetti (I)

Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Paolo Pelosi (P)

Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, 16132 Genoa, Italy.
Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.

Matteo Bassetti (M)

Infectious Diseases Unit, San Martino Policlinico Hospital-IRCCS for Oncology and Neurosciences, 16132 Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, 16132 Genoa, Italy.

Classifications MeSH