Genome-Wide Association Study and Pathway Analysis for Heterophil/Lymphocyte (H/L) Ratio in Chicken.
GWAS
H/L
disease-resistant breeding
pathway
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
27 08 2020
27 08 2020
Historique:
received:
12
07
2020
revised:
19
08
2020
accepted:
19
08
2020
entrez:
2
9
2020
pubmed:
2
9
2020
medline:
1
4
2021
Statut:
epublish
Résumé
Disease control and prevention have been critical factors in the dramatic growth of the poultry industry. Disease resistance in chickens can be improved through genetic selection for immunocompetence. The heterophil/lymphocyte ratio (H/L) in the blood reflects the immune system status of chickens. Our objective was to conduct a genome-wide association study (GWAS) and pathway analysis to identify possible biological mechanisms involved in H/L traits. In this study, GWAS for H/L was performed in 1317 Cobb broilers to identify significant single-nucleotide polymorphisms (SNPs) associated with H/L. Eight SNPs (
Identifiants
pubmed: 32867375
pii: genes11091005
doi: 10.3390/genes11091005
pmc: PMC7563235
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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