Characterizing chromatin packing scaling in whole nuclei using interferometric microscopy.
Journal
Optics letters
ISSN: 1539-4794
Titre abrégé: Opt Lett
Pays: United States
ID NLM: 7708433
Informations de publication
Date de publication:
01 Sep 2020
01 Sep 2020
Historique:
entrez:
2
9
2020
pubmed:
2
9
2020
medline:
29
6
2021
Statut:
ppublish
Résumé
Chromatin is the macromolecular assembly containing the cell's genetic information, and its architectural conformation facilitates accessibility to activation sites and thus gene expression. We have developed an analytical framework to quantify chromatin structure with spectral microscopy. Chromatin structure can be described as a mass fractal, with packing scaling
Identifiants
pubmed: 32870863
pii: 437557
doi: 10.1364/OL.400231
pmc: PMC7951997
mid: NIHMS1674175
doi:
Substances chimiques
Chromatin
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4810-4813Subventions
Organisme : NCI NIH HHS
ID : R01 CA200064
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA225002
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA228272
Pays : United States
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