A Polyvinyl Alcohol-Based Thermochromic Material for Ultrasound Therapy Phantoms.

High-intensity focused ultrasound Phantom Quality assurance Thermal ablation Thermochromic material

Journal

Ultrasound in medicine & biology
ISSN: 1879-291X
Titre abrégé: Ultrasound Med Biol
Pays: England
ID NLM: 0410553

Informations de publication

Date de publication:
11 2020
Historique:
received: 01 06 2020
revised: 27 07 2020
accepted: 31 07 2020
pubmed: 3 9 2020
medline: 27 8 2021
entrez: 3 9 2020
Statut: ppublish

Résumé

Temperature estimation is a fundamental step in assessment of the efficacy of thermal therapy. A thermochromic material sensitive within the temperature range 52.5°C-75°C has been developed. The material is based on polyvinyl alcohol cryogel with the addition of a commercial thermochromic ink. It is simple to manufacture, low cost, non-toxic and versatile. The thermal response of the material was evaluated using multiple methods, including immersion in a temperature-controlled water bath, a temperature-controlled heated needle and high-intensity focused ultrasound (HIFU) sonication. Changes in colour were evaluated using both RGB (red, green, blue) maps and pixel intensities. Acoustic and thermal properties of the material were measured. Thermo-acoustic simulations were run with an open-source software, and results were compared with the HIFU experiments, showing good agreement. The material has good potential for the development of ultrasound therapy phantoms.

Identifiants

pubmed: 32873445
pii: S0301-5629(20)30347-1
doi: 10.1016/j.ultrasmedbio.2020.07.032
pii:
doi:

Substances chimiques

Polyvinyl Alcohol 9002-89-5

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3135-3144

Informations de copyright

Copyright © 2020 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest disclosure The authors declare no competing interests.

Auteurs

Simone Ambrogio (S)

Medical Physics Department, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; Ultrasound and Underwater Acoustics, National Physical Laboratory, Hampton Road, Teddington, United Kingdom. Electronic address: Simone.Ambrogio@gstt.nhs.uk.

Raphaela de Melo Baêsso (RM)

Ultrasound and Underwater Acoustics, National Physical Laboratory, Hampton Road, Teddington, United Kingdom.

Alberto Gomis (A)

Ultrasound and Underwater Acoustics, National Physical Laboratory, Hampton Road, Teddington, United Kingdom; Joint Department of Physics at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom.

Ian Rivens (I)

Joint Department of Physics at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom.

Gail Ter Haar (GT)

Joint Department of Physics at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom.

Bajram Zeqiri (B)

Ultrasound and Underwater Acoustics, National Physical Laboratory, Hampton Road, Teddington, United Kingdom.

Kumar V Ramnarine (KV)

Medical Physics Department, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.

Fiammetta Fedele (F)

Medical Physics Department, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.

Piero Miloro (P)

Ultrasound and Underwater Acoustics, National Physical Laboratory, Hampton Road, Teddington, United Kingdom.

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Classifications MeSH