Tumour spillage of the pleomorphic adenoma of the parotid gland: A proposal for intraoperative measures.
Adenoma, Pleomorphic
/ pathology
Algorithms
Contraindications, Procedure
Dissection
/ adverse effects
Drug Combinations
Fibrinogen
/ administration & dosage
Humans
Intraoperative Care
/ methods
Intraoperative Complications
/ pathology
Neoplasm Recurrence, Local
/ etiology
Neoplasm Seeding
Parotid Gland
/ surgery
Parotid Neoplasms
/ surgery
Postoperative Period
Pseudopodia
Rupture
/ therapy
Salivary Gland Neoplasms
/ pathology
Surgical Wound
Therapeutic Irrigation
/ adverse effects
Thrombin
/ administration & dosage
Truth Disclosure
Journal
Oral oncology
ISSN: 1879-0593
Titre abrégé: Oral Oncol
Pays: England
ID NLM: 9709118
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
25
08
2020
accepted:
25
08
2020
pubmed:
3
9
2020
medline:
23
9
2021
entrez:
3
9
2020
Statut:
ppublish
Résumé
Intraoperative rupture of a pleomorphic adenoma capsule with potential tumor spillage into the surgical field is thought to occur in approximately 5% of cases and has traditionally been recognized as one of the major causes of recurrence. It seems that recurrence of a pleomorphic adenoma is a multifactorial event, being related to surgery (capsular exposure, tumor spillage) and tumor-related factors (histologic subtype, incomplete capsule, pseudopodia, satellites). The exact quantities of these ingredients in the recipe of recurrence, as well as possible interactions between them (e.g. the potentially increased fragility of myxoid pleomorphic adenomas; satellites or pseudopodia being cut off the tumor specimen during an extremely narrow extracapsular dissection) remain unclear. A thorough literature search did not reveal any proposed algorithms for the intraoperative management of a capsular tear. The aim of this short communication is to present our department's experience-based proposal for intraoperative measures in the case of macroscopic rupture and tumor spillage of a parotid gland pleomorphic adenoma.
Identifiants
pubmed: 32873463
pii: S1368-8375(20)30422-X
doi: 10.1016/j.oraloncology.2020.104986
pii:
doi:
Substances chimiques
Drug Combinations
0
TachoSil
0
Fibrinogen
9001-32-5
Thrombin
EC 3.4.21.5
Types de publication
Letter
Langues
eng
Sous-ensembles de citation
IM
Pagination
104986Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.