Correlation between left atrial spontaneous echocardiographic contrast and 5-year stroke/death in patients with non-valvular atrial fibrillation.
Aged
Aged, 80 and over
Anti-Arrhythmia Agents
/ therapeutic use
Anticoagulants
/ therapeutic use
Atrial Fibrillation
/ complications
Echocardiography, Transesophageal
Female
Heart Atria
/ diagnostic imaging
Humans
Longitudinal Studies
Male
Middle Aged
Platelet Aggregation Inhibitors
/ therapeutic use
Predictive Value of Tests
Prognosis
Prospective Studies
Risk Assessment
Risk Factors
Stroke
/ diagnosis
Time Factors
Atrial fibrillation
CHA(2)DS(2)-VASc score
Echocardiography
Fibrillation atriale
Reassessment
Reclassification
Risque thrombo-embolique
Thromboembolic risk
Échocardiographie
Journal
Archives of cardiovascular diseases
ISSN: 1875-2128
Titre abrégé: Arch Cardiovasc Dis
Pays: Netherlands
ID NLM: 101465655
Informations de publication
Date de publication:
Historique:
received:
26
11
2019
revised:
17
02
2020
accepted:
18
02
2020
pubmed:
3
9
2020
medline:
30
9
2020
entrez:
3
9
2020
Statut:
ppublish
Résumé
Transthoracic echocardiography (TTE) and transoesophageal echocardiography (TOE) can be used to detect the presence of left atrial thrombus and left atrial spontaneous echocardiographic contrast (LASEC). To evaluate the prognostic value of TTE and TOE in predicting stroke and all-cause death at 5-year follow-up in patients with non-valvular atrial fibrillation (NVAF). This study included patients hospitalised with electrocardiography-diagnosed NVAF in Saint-Antoine University Hospital, Paris, between July 1998 and December 2011, who underwent TTE and TOE evaluation within 24hours of admission. Cox proportional-hazards models were used to identify predictors of the composite outcome (stroke or all-cause death). During 5 years of follow-up, stroke/death occurred in 185/903 patients (20.5%). By multivariable analysis, independent predictors of stroke/death were CHA In this retrospective monocentric study, the presence of moderate/severe LASEC was an independent predictor of stroke/death at 5-year follow-up in patients with NVAF. The inclusion of LASEC in stroke risk scores could modestly improve risk stratification.
Sections du résumé
BACKGROUND
BACKGROUND
Transthoracic echocardiography (TTE) and transoesophageal echocardiography (TOE) can be used to detect the presence of left atrial thrombus and left atrial spontaneous echocardiographic contrast (LASEC).
AIM
OBJECTIVE
To evaluate the prognostic value of TTE and TOE in predicting stroke and all-cause death at 5-year follow-up in patients with non-valvular atrial fibrillation (NVAF).
METHODS
METHODS
This study included patients hospitalised with electrocardiography-diagnosed NVAF in Saint-Antoine University Hospital, Paris, between July 1998 and December 2011, who underwent TTE and TOE evaluation within 24hours of admission. Cox proportional-hazards models were used to identify predictors of the composite outcome (stroke or all-cause death).
RESULTS
RESULTS
During 5 years of follow-up, stroke/death occurred in 185/903 patients (20.5%). By multivariable analysis, independent predictors of stroke/death were CHA
CONCLUSIONS
CONCLUSIONS
In this retrospective monocentric study, the presence of moderate/severe LASEC was an independent predictor of stroke/death at 5-year follow-up in patients with NVAF. The inclusion of LASEC in stroke risk scores could modestly improve risk stratification.
Identifiants
pubmed: 32873521
pii: S1875-2136(20)30123-6
doi: 10.1016/j.acvd.2020.02.003
pii:
doi:
Substances chimiques
Anti-Arrhythmia Agents
0
Anticoagulants
0
Platelet Aggregation Inhibitors
0
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
525-533Informations de copyright
Copyright © 2020. Published by Elsevier Masson SAS.