Heritability of overlapping impulsivity and compulsivity dimensional phenotypes.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
01 09 2020
01 09 2020
Historique:
received:
31
01
2020
accepted:
06
08
2020
entrez:
3
9
2020
pubmed:
3
9
2020
medline:
9
3
2021
Statut:
epublish
Résumé
Impulsivity and compulsivity are traits relevant to a range of mental health problems and have traditionally been conceptualised as distinct constructs. Here, we reconceptualised impulsivity and compulsivity as partially overlapping phenotypes using a bifactor modelling approach and estimated heritability for their shared and unique phenotypic variance within a classical twin design. Adult twin pairs (N = 173) completed self-report questionnaires measuring psychological processes related to impulsivity and compulsivity. We fitted variance components models to three uncorrelated phenotypic dimensions: a general impulsive-compulsive dimension; and two narrower phenotypes related to impulsivity and obsessiveness.There was evidence of moderate heritability for impulsivity (A
Identifiants
pubmed: 32873811
doi: 10.1038/s41598-020-71013-x
pii: 10.1038/s41598-020-71013-x
pmc: PMC7463011
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Twin Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
14378Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 110049/Z/15/Z
Pays : United Kingdom
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