Scientific Opinion of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on the genotoxic potential of triazine amine (metabolite common to several sulfonylurea active substances).
AE F059411
Aminotriazine
CGA 150 829
IN‐A4098
chromosome aberration
groundwater
mutagenicity
pesticide
residue
Journal
EFSA journal. European Food Safety Authority
ISSN: 1831-4732
Titre abrégé: EFSA J
Pays: United States
ID NLM: 101642076
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
entrez:
3
9
2020
pubmed:
3
9
2020
medline:
3
9
2020
Statut:
epublish
Résumé
The Panel received a mandate from the European Commission to assess the genotoxic potential of triazine amine based on available information submitted by the applicants. Available information includes experimental genotoxicity data on triazine amine, Quantitative Structure-Activity Relationship (QSAR) analysis and read across with structurally similar compounds. Based on the overall weight of evidence, the Panel, in agreement with the cross-cutting Working Group Genotoxicity, concluded that there is no concern for the potential of triazine amine to induce gene mutations and clastogenicity; however, the potential to induce aneugenicity was not adequately investigated. For a conclusion, an
Identifiants
pubmed: 32874265
doi: 10.2903/j.efsa.2020.6053
pii: EFS26053
pmc: PMC7447991
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e06053Informations de copyright
© 2020 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.
Références
EFSA J. 2017 Dec 18;15(12):e05113
pubmed: 32625393