Health-related quality of life and its associated predictors in patients with oral lichen planus: a cross-sectional study.
Chronic Oral Mucosal Disease Questionnaire
Oral lichen planus
quality of life
Journal
International dental journal
ISSN: 1875-595X
Titre abrégé: Int Dent J
Pays: England
ID NLM: 0374714
Informations de publication
Date de publication:
01 Sep 2020
01 Sep 2020
Historique:
entrez:
3
9
2020
pubmed:
3
9
2020
medline:
3
9
2020
Statut:
aheadofprint
Résumé
To investigate levels of quality of life (QoL) and determine associated predictors in patients with oral lichen planus (OLP). A total of 300 patients with OLP at one tertiary Oral Medicine clinic in the UK were recruited in a cross-sectional study from January 2018 to July 2019. The 15-item Chronic Oral Mucosal Disease Questionnaire (COMDQ-15) and 14-item Oral Health Impact Profile (OHIP-14) were used to assess the level of QoL related to OLP. A number of potential determinants were considered, including patient demographics, treatment, the severity of oral symptoms, the clinical activity of the disease, and the patient psychological status, which were measured using the pain-Numerical Rating Scale, the Oral Disease Severity Score, the Hospital Anxiety and Depression Scale, and the 10-item Perceived Stress Scale. Multivariate linear regression was employed to identify independent determinants associated with overall and aspects of QoL. On multivariate analyses, after adjusting for confounding variables, the QoL levels in patients with OLP were significantly associated with levels of oral pain, anxiety, stress and use of topical corticosteroids. The COMDQ-15 instrument performed better than OHIP-14 at capturing the association between QoL and pain and disease activity in patients with OLP. Clinicians should expect reduced QoL in OLP patients with high pain levels, high anxiety levels, high perceived stress and use of topical corticosteroids. The COMDQ-15 is best suited to measure QoL in this population.
Identifiants
pubmed: 32875594
doi: 10.1111/idj.12607
pmc: PMC9275316
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Faculty of Dentistry, Chulalongkorn University
Organisme : The NIHR Clinical Research Network Portfolio
Organisme : The NIHR University College London Hospitals Biomedical Research Centre
Informations de copyright
© 2020 FDI World Dental Federation.
Références
Oral Dis. 2006 Sep;12(5):463-8
pubmed: 16910916
J Appl Oral Sci. 2018 Jan 18;26:e20170146
pubmed: 29364344
Clin Oral Investig. 2020 Jan;24(1):301-308
pubmed: 31098713
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jan;105(1):51-8
pubmed: 18155609
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 May;111(5):578-86, 586.e1-2
pubmed: 21429772
J Oral Pathol Med. 2018 Mar;47(3):228-239
pubmed: 28622422
J Psychosom Res. 2002 Feb;52(2):69-77
pubmed: 11832252
Community Dent Oral Epidemiol. 1997 Aug;25(4):284-90
pubmed: 9332805
J Oral Pathol Med. 2020 Jan;49(1):55-62
pubmed: 31605549
Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Mar;123(3):338-349
pubmed: 28094217
Ann Saudi Med. 2019 Jan-Feb;39(1):48-55
pubmed: 30712051
BMC Oral Health. 2018 Dec 27;18(1):226
pubmed: 30587180
Oral Oncol. 2019 Sep;96:121-130
pubmed: 31422203
Eur J Dent. 2015 Oct-Dec;9(4):564-572
pubmed: 26929697
Oral Dis. 2020 Oct;26(7):1464-1473
pubmed: 32363637
Oral Dis. 2011 Apr;17(3):265-9
pubmed: 20860762
Perm J. 2014 Winter;18(1):e123-7
pubmed: 24626087
Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11:S240-52
pubmed: 22588748
Clin Oral Investig. 2019 Dec;23(12):4441-4448
pubmed: 30989337
Oral Dis. 2020 Jan;26(1):96-110
pubmed: 31650646
Oral Dis. 2019 Sep;25(6):1564-1572
pubmed: 31006147
Cochrane Database Syst Rev. 2011 Jul 06;(7):CD001168
pubmed: 21735381
J Oral Pathol Med. 2003 Oct;32(9):507-12
pubmed: 12969224
Oral Dis. 2005 Nov;11(6):338-49
pubmed: 16269024
J Oral Pathol Med. 2018 Jan;47(1):60-65
pubmed: 28766765
Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Mar;117(3):319-23
pubmed: 24144994
Br J Dermatol. 2007 Oct;157(4):765-70
pubmed: 17711534
J Eval Clin Pract. 2010 Feb;16(1):111-3
pubmed: 20367822
J Oral Maxillofac Surg. 2014 Aug;72(8):1517-22
pubmed: 25037185
J Affect Disord. 2016 Oct;203:176-183
pubmed: 27295374
Oral Dis. 2021 May;27(4):813-828
pubmed: 32144836