A Role for Isatin Azomethine Imines as a Dipolarophile in Cycloaddition Reactions.
Journal
Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393
Informations de publication
Date de publication:
18 09 2020
18 09 2020
Historique:
pubmed:
3
9
2020
medline:
3
9
2020
entrez:
3
9
2020
Statut:
ppublish
Résumé
An unusual [2 + 3] cycloaddition of isatin azomethine imines (AIs) and in situ generated azaoxyallyl cations has been developed. It is the first example where AIs serve as the [C,O] 2-atom synthon in organic synthesis. This work not only reveals a new role of isatin AIs in cycloaddition reaction but also provides an efficient access to unprecedented spiroheterocycle compounds.
Identifiants
pubmed: 32875804
doi: 10.1021/acs.orglett.0c02705
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM