Neuroinvasive West Nile Infection with an Unusual Clinical Presentation: A Single-Center Case Series.
Flavivirus
West Nile Virus
artropodes
mosquitos
neuroinvasiveness
vector
Journal
Tropical medicine and infectious disease
ISSN: 2414-6366
Titre abrégé: Trop Med Infect Dis
Pays: Switzerland
ID NLM: 101709042
Informations de publication
Date de publication:
31 Aug 2020
31 Aug 2020
Historique:
received:
16
07
2020
revised:
14
08
2020
accepted:
25
08
2020
entrez:
4
9
2020
pubmed:
4
9
2020
medline:
4
9
2020
Statut:
epublish
Résumé
The 2018 West Nile Virus (WNV) season in Europe was characterized by an extremely high infection rate and an exceptionally higher burden when compared to previous seasons. Overall, there was a 10.9-fold increase in incidence in Italy, with 577 human cases, 230 WNV neuroinvasive diseases (WNNV) and 42 WNV-attributed deaths. Methods: in this paper we retrospectively reported the neurological presentation of 7 patients admitted to University Hospital of Udine with a diagnosis of WNNV, especially focusing on two patients who presented with atypical severe brain stem involvement. Conclusions: the atypical features of some of these forms highlight the necessity to stay vigilant and suspect the diagnosis when confronted with neurological symptoms. We strongly encourage clinicians to consider WNNV in patients presenting with unexplained neurological symptoms in mild climate-areas at risk.
Identifiants
pubmed: 32878269
pii: tropicalmed5030138
doi: 10.3390/tropicalmed5030138
pmc: PMC7558676
pii:
doi:
Types de publication
Case Reports
Langues
eng
Références
Virology. 2005 May 25;336(1):70-82
pubmed: 15866072
JAMA. 2013 Jul 17;310(3):308-15
pubmed: 23860989
Euro Surveill. 2018 Aug;23(32):
pubmed: 30107869
J Infect Dis. 2013 Oct 1;208(7):1086-92
pubmed: 23821721
Viruses. 2013 Sep 25;5(10):2329-48
pubmed: 24072061
Neurol Neuroimmunol Neuroinflamm. 2019 Nov 22;7(1):
pubmed: 31757817
J Gen Virol. 2008 Feb;89(Pt 2):467-473
pubmed: 18198377
AJNR Am J Neuroradiol. 2005 Aug;26(7):1698-701
pubmed: 16091517
Cerebellum. 2015 Jun;14(3):317-40
pubmed: 25520275
Front Neurol. 2018 Oct 16;9:864
pubmed: 30386288
Annu Rev Virol. 2018 Sep 29;5(1):255-272
pubmed: 30265628
Nat Rev Microbiol. 2013 Feb;11(2):115-28
pubmed: 23321534
Curr Infect Dis Rep. 2013 Nov 15;:
pubmed: 24234656
J Child Neurol. 2006 Jul;21(7):623-5
pubmed: 16970859
Lancet Infect Dis. 2004 Sep;4(9):547-56
pubmed: 15336221
J Clin Microbiol. 2016 Sep;54(9):2294-7
pubmed: 27335150