Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
02 09 2020
Historique:
received: 04 09 2019
accepted: 12 06 2020
entrez: 4 9 2020
pubmed: 4 9 2020
medline: 30 9 2020
Statut: epublish

Résumé

The hypothalamic suprachiasmatic (SCN) clock contains several neurochemically defined cell groups that contribute to the genesis of circadian rhythms. Using cell-specific and genetically targeted approaches we have confirmed an indispensable role for vasoactive intestinal polypeptide-expressing SCN (SCN

Identifiants

pubmed: 32879310
doi: 10.1038/s41467-020-17197-2
pii: 10.1038/s41467-020-17197-2
pmc: PMC7468160
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4410

Subventions

Organisme : NIDA NIH HHS
ID : T32 DA007262
Pays : United States
Organisme : NIDDK NIH HHS
ID : R56 DK104999
Pays : United States
Organisme : NINDS NIH HHS
ID : R56 NS036607
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS073613
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS103161
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS092652
Pays : United States
Organisme : NIDDK NIH HHS
ID : K08 DK071561
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS036607
Pays : United States
Organisme : NIA NIH HHS
ID : R03 AG062883
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK046200
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS091126
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS103842
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK104999
Pays : United States
Organisme : NINDS NIH HHS
ID : P30 NS061800
Pays : United States
Organisme : NIMH NIH HHS
ID : K99 MH103399
Pays : United States
Organisme : NINDS NIH HHS
ID : F32 NS084582
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK057521
Pays : United States

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Auteurs

William D Todd (WD)

Department of Zoology and Physiology, Program in Neuroscience, University of Wyoming, Laramie, WY, 82071, USA.

Anne Venner (A)

Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02215, USA.

Christelle Anaclet (C)

Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA, 01605, USA.

Rebecca Y Broadhurst (RY)

Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02215, USA.

Roberto De Luca (R)

Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02215, USA.

Sathyajit S Bandaru (SS)

Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02215, USA.

Lindsay Issokson (L)

Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02215, USA.

Lauren M Hablitz (LM)

Oregon Institute for Occupational Health Sciences and Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97239, USA.

Olga Cravetchi (O)

Oregon Institute for Occupational Health Sciences and Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97239, USA.

Elda Arrigoni (E)

Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02215, USA.

John N Campbell (JN)

Department of Biology, University of Virginia, Charlottesville, VA, USA.

Charles N Allen (CN)

Oregon Institute for Occupational Health Sciences and Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, 97239, USA.

David P Olson (DP)

Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA.

Patrick M Fuller (PM)

Department of Neurology, Beth Israel Deaconess Medical Center, Division of Sleep Medicine, Harvard Medical School, Boston, MA, 02215, USA. pfuller@bidmc.harvard.edu.

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