Violet-light suppression of thermogenesis by opsin 5 hypothalamic neurons.

Adipose Tissue, Brown / innervation Animals Body Temperature Cold Temperature Color Cyclic AMP / metabolism Female Light Male Membrane Proteins / deficiency Mice Neurons / metabolism Opsins / deficiency Preoptic Area / cytology Thermogenesis / genetics

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
09 2020
Historique:
received: 19 02 2020
accepted: 04 08 2020
pubmed: 4 9 2020
medline: 30 10 2020
entrez: 4 9 2020
Statut: ppublish

Résumé

The opsin family of G-protein-coupled receptors are used as light detectors in animals. Opsin 5 (also known as neuropsin or OPN5) is a highly conserved opsin that is sensitive to visible violet light

Identifiants

DOI: 10.1038/s41586-020-2683-0 PMID: 32879486 PMC: PMC8130195
pubmed: 32879486
doi: 10.1038/s41586-020-2683-0
pii: 10.1038/s41586-020-2683-0
pmc: PMC8130195
mid: NIHMS1617991
doi:

Substances chimiques

Membrane Proteins 0
OPN5 protein, mouse 0
Opsins 0
Cyclic AMP E0399OZS9N

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

420-425

Subventions

Organisme : NEI NIH HHS
ID : R01 EY032029
Pays : United States
Organisme : American Heart Association-American Stroke Association
ID : 18CDA34080527
Pays : United States
Organisme : NEI NIH HHS
ID : P30 EY001730
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY027711
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY026921
Pays : United States
Organisme : NIGMS NIH HHS
ID : 5T32GM063483
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK089503
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM063483
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY027077
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM124246
Pays : United States

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Références

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Auteurs

Kevin X Zhang (KX)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Molecular and Developmental Biology Graduate Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Medical Scientist Training Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
ORCID: 0000-0002-6028-6536

Shane D'Souza (S)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Molecular and Developmental Biology Graduate Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
ORCID: 0000-0001-6344-1434

Brian A Upton (BA)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Molecular and Developmental Biology Graduate Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Medical Scientist Training Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
ORCID: 0000-0003-4544-6869

Stace Kernodle (S)

Department of Surgery, University of Michigan, School of Public Health, Ann Arbor, MI, USA.

Shruti Vemaraju (S)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Gowri Nayak (G)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
ORCID: 0000-0002-5106-5192

Kevin D Gaitonde (KD)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Molecular and Developmental Biology Graduate Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Medical Scientist Training Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
ORCID: 0000-0002-2536-5132

Amanda L Holt (AL)

Department of Physics, Yale University, New Haven, CT, USA.

Courtney D Linne (CD)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Molecular and Developmental Biology Graduate Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Medical Scientist Training Program, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
ORCID: 0000-0002-2493-8197

April N Smith (AN)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Nathan T Petts (NT)

Division of Clinical Engineering, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Matthew Batie (M)

Division of Clinical Engineering, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Rajib Mukherjee (R)

Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Durgesh Tiwari (D)

Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Ethan D Buhr (ED)

Department of Ophthalmology, University of Washington Medical School, Seattle, WA, USA.

Russell N Van Gelder (RN)

Department of Ophthalmology, University of Washington Medical School, Seattle, WA, USA.
Department of Biological Structure, University of Washington Medical School, Seattle, WA, USA.
Department of Pathology, University of Washington Medical School, Seattle, WA, USA.

Christina Gross (C)

Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
ORCID: 0000-0001-6057-2527

Alison Sweeney (A)

Department of Physics, Yale University, New Haven, CT, USA.

Joan Sanchez-Gurmaches (J)

Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
ORCID: 0000-0003-1854-7832

Randy J Seeley (RJ)

Department of Surgery, University of Michigan, School of Public Health, Ann Arbor, MI, USA.
Department of Internal Medicine, University of Michigan, School of Public Health, Ann Arbor, MI, USA.
ORCID: 0000-0002-3721-5625

Richard A Lang (RA)

The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Richard.Lang@cchmc.org.
Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Richard.Lang@cchmc.org.
Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Richard.Lang@cchmc.org.
Department of Ophthalmology, University of Cincinnati, College of Medicine, Cincinnati, OH, USA. Richard.Lang@cchmc.org.
ORCID: 0000-0002-5212-254X

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Classifications MeSH

questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Tissu adipeux brun › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Eucaryotes › Animaux › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Phénomènes physiologiques › Température du corps › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Température › Basse température › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Phénomènes physiques › Phénomènes optiques › Couleur › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › AMP cyclique › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Phénomènes physiques › Rayonnement › Rayonnement non ionisant › Lumière › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Cellules › Neurones › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Pigments rétiniens › Opsines › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Diencéphale › Hypothalamus › Hypothalamus antérieur › Aire préoptique › Violet-light suppression of thermogenesis by...
questionsmedicales.fr › Phénomènes biologiques › Adaptation biologique › Adaptation physiologique › Régulation de la température corporelle › Thermogenèse › Violet-light suppression of thermogenesis by...