A cross-national study of depression in preclinical dementia: A COSMIC collaboration study.
dementia
depression
incidence
Journal
Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
17
02
2020
revised:
15
05
2020
accepted:
23
07
2020
pubmed:
4
9
2020
medline:
28
9
2021
entrez:
4
9
2020
Statut:
ppublish
Résumé
Depression commonly accompanies Alzheimer's disease, but the nature of this association remains uncertain. Longitudinal data from the COSMIC consortium were harmonized for eight population-based cohorts from four continents. Incident dementia was diagnosed in 646 participants, with a median follow-up time of 5.6 years to diagnosis. The association between years to dementia diagnosis and successive depressive states was assessed using a mixed effect logistic regression model. A generic inverse variance method was used to group study results, construct forest plots, and generate heterogeneity statistics. A common trajectory was observed showing an increase in the incidence of depression as the time to dementia diagnosis decreased despite cross-national variability in depression rates. The results support the hypothesis that depression occurring in the preclinical phases of dementia is more likely to be attributable to dementia-related brain changes than environment or reverse causality.
Identifiants
pubmed: 32881298
doi: 10.1002/alz.12149
pmc: PMC7666102
mid: NIHMS1621194
doi:
Types de publication
Journal Article
Multicenter Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1544-1552Subventions
Organisme : NIA NIH HHS
ID : R01 AG012975
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG023651
Pays : United States
Organisme : NIA NIH HHS
ID : RF1 AG057531
Pays : United States
Informations de copyright
© 2020 the Alzheimer's Association.
Références
J Glob Health. 2019 Jun;9(1):011001
pubmed: 30997043
Neurology. 2010 Jul 6;75(1):21-6
pubmed: 20603481
Am J Geriatr Psychiatry. 2018 Aug;26(8):819-827
pubmed: 29960668
J Psychiatry Neurosci. 2004 Nov;29(6):417-26
pubmed: 15644983
Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jun 3;43:203-8
pubmed: 23276885
Neuroepidemiology. 1992;11 Suppl 1:84-7
pubmed: 1603256
Arch Gen Psychiatry. 2008 May;65(5):542-50
pubmed: 18458206
Psychol Med. 1991 Feb;21(1):225-36
pubmed: 2047500
Biol Psychiatry. 2002 Aug 1;52(3):243-52
pubmed: 12182930
Alzheimers Dement. 2018 Jun;14(6):703-706
pubmed: 29842864
Int J Geriatr Psychiatry. 2011 Sep;26(9):944-51
pubmed: 21845597
Int J Geriatr Psychiatry. 2009 Nov;24(11):1277-84
pubmed: 19340894
Biol Psychiatry. 2003 Aug 1;54(3):353-62
pubmed: 12893110
Int Psychogeriatr. 2010 Dec;22(8):1248-64
pubmed: 20637138
J Alzheimers Dis. 2014;42(3):739-55
pubmed: 24946876
Br J Psychiatry. 2013 May;202(5):329-35
pubmed: 23637108
Br J Psychiatry. 1996 Mar;168(3):287-91
pubmed: 8833681
Br J Psychiatry. 2001 Sep;179:250-4
pubmed: 11532803
Am J Psychiatry. 1994 Jul;151(7):1006-9
pubmed: 8010355
J Am Geriatr Soc. 2003 Feb;51(2):169-77
pubmed: 12558712
Neurology. 2010 Jul 6;75(1):35-41
pubmed: 20603483
Dement Geriatr Cogn Disord. 2002;13(1):8-12
pubmed: 11731709
J Nutr Health Aging. 2011 Aug;15(8):609-17
pubmed: 21968854
Arch Gen Psychiatry. 2008 Apr;65(4):439-45
pubmed: 18391132
Acta Psychiatr Scand. 2006 Dec;114(6):398-410
pubmed: 17087788
J Clin Psychiatry. 2016 Mar;77(3):e305-11
pubmed: 26891108
BMJ. 2010 Aug 05;341:c3885
pubmed: 20688841
Psychiatry Investig. 2018 Aug;15(8):767-774
pubmed: 30086611
BMC Neurol. 2013 Nov 06;13:165
pubmed: 24195705
Lancet Psychiatry. 2016 Jul;3(7):628-35
pubmed: 27138970
BMC Geriatr. 2013 Sep 24;13:98
pubmed: 24063518
Int J Epidemiol. 2014 Apr;43(2):365-406
pubmed: 24366490