The nitric oxide dependence of cutaneous microvascular function to independent and combined hypoxic cold exposure.

Humans Hypoxia Microdialysis NG-Nitroarginine Methyl Ester / pharmacology Nitric Oxide Nitric Oxide Synthase Regional Blood Flow Skin Skin Physiological Phenomena Vasodilation
cold hypoxia microdialysis nitric oxide vasoconstriction vasodilatation

Journal

Journal of applied physiology (Bethesda, Md. : 1985)
ISSN: 1522-1601
Titre abrégé: J Appl Physiol (1985)
Pays: United States
ID NLM: 8502536

Informations de publication

Date de publication:
01 10 2020
Historique:
pubmed: 4 9 2020
medline: 24 6 2021
entrez: 4 9 2020
Statut: ppublish

Résumé

Hypoxic modulation of nitric oxide (NO) production pathways in the cutaneous microvasculature and its interaction with cold-induced reflex vasoconstriction, independent of local cooling, have yet to be identified. This study assessed the contribution of NO to nonglabrous microvasculature perfusion during hypoxia and whole body cooling with concomitant inhibition of NO synthase [NOS; via

Identifiants

DOI: 10.1152/japplphysiol.00487.2020 PMID: 32881624
pubmed: 32881624
doi: 10.1152/japplphysiol.00487.2020
doi:

Substances chimiques

Nitric Oxide 31C4KY9ESH
Nitric Oxide Synthase EC 1.14.13.39
NG-Nitroarginine Methyl Ester V55S2QJN2X

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

947-956

Auteurs

Josh T Arnold (JT)

Environmental Ergonomics Research Centre, Loughborough University, Loughborough, United Kingdom.
ORCID: 0000-0001-9905-2000

Alex B Lloyd (AB)

Environmental Ergonomics Research Centre, Loughborough University, Loughborough, United Kingdom.
ORCID: 0000-0003-0657-3582

Stephen J Bailey (SJ)

School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom.

Tomomi Fujimoto (T)

Department of Health and Sports, Niigata University of Health and Welfare, Niigata, Japan.
Institute for Human Movement and Medical Science, Niigata University of Health and Welfare, Niigata, Japan.
Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.

Ryoko Matsutake (R)

Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.

Masataka Takayanagi (M)

Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.

Takeshi Nishiyasu (T)

Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.

Naoto Fujii (N)

Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan.
ORCID: 0000-0001-9696-8291

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Signes et symptômes respiratoires › Hypoxie › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Microdialyse › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés diaminés › L-NAME › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Monoxyde d'azote › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxidoreductases acting on CH-NH2 group donors › Amino-acid oxidoreductases › Nitric oxide synthase › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Circulation sanguine › Débit sanguin régional › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › Système tégumentaire › Peau › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › Phénomènes physiologiques du système tégumentaire › Phénomènes physiologiques de la peau › The nitric oxide dependence of cutaneous...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Hémodynamique › Vasodilatation › The nitric oxide dependence of cutaneous...