5-(
DFT calculations
electron-induced degradation
modified nucleobases
radiosensitizer
uracil derivatives
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
01 Sep 2020
01 Sep 2020
Historique:
received:
21
07
2020
revised:
18
08
2020
accepted:
28
08
2020
entrez:
5
9
2020
pubmed:
5
9
2020
medline:
30
3
2021
Statut:
epublish
Résumé
Hypoxia-a hallmark of solid tumors-dramatically impairs radiotherapy, one of the most common anticancer modalities. The adverse effect of the low-oxygen state can be eliminated by the concomitant use of a hypoxic cell radiosensitizer. In the present paper, we show that 5-(
Identifiants
pubmed: 32883013
pii: ijms21176352
doi: 10.3390/ijms21176352
pmc: PMC7504071
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Radiation-Sensitizing Agents
0
Uracil
56HH86ZVCT
DNA
9007-49-2
5-aminouracil
R2O7EKY9G9
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Narodowe Centrum Nauki
ID : UMO-2014/14/A/ST4/00405
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