A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort.

Body Mass Index Cohort Studies Europe Female Humans Male Obesity, Abdominal / mortality Proportional Hazards Models Risk Factors Waist Circumference / physiology Waist-Hip Ratio

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
03 09 2020
Historique:
received: 12 02 2020
accepted: 06 08 2020
entrez: 5 9 2020
pubmed: 5 9 2020
medline: 9 3 2021
Statut: epublish

Résumé

Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proportional hazards models adjusted for other risk factors. During a mean follow-up of 16.1 years, 38,178 participants died. Combining in one model BMI and a strongly correlated waist index altered the association patterns with mortality, to a predominantly negative association for BMI and a stronger positive association for the waist index, while combining BMI with the uncorrelated A Body Shape Index (ABSI) preserved the association patterns. Sex-specific cohort-wide quartiles of waist indices correlated with BMI could not separate high-risk from low-risk individuals within underweight (BMI < 18.5 kg/m

Identifiants

DOI: 10.1038/s41598-020-71302-5 PMID: 32883969 PMC: PMC7471961
pubmed: 32883969
doi: 10.1038/s41598-020-71302-5
pii: 10.1038/s41598-020-71302-5
pmc: PMC7471961
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

14541

Subventions

Organisme : Medical Research Council
ID : MC_UU_00006/1
Pays : United Kingdom
Organisme : Cancer Research UK
ID : C570/A16491
Pays : United Kingdom
Organisme : Cancer Research UK
ID : C8221/A19170
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_12015/1
Pays : United Kingdom
Organisme : Cancer Research UK
ID : 24390
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N003284/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0401527
Pays : United Kingdom
Organisme : Cancer Research UK
ID : 14136
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M012190/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G1000143
Pays : United Kingdom

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Auteurs

Sofia Christakoudi (S)

Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, St Mary's Campus, London, W2 1PG, UK. s.christakoudi@imperial.ac.uk.
MRC Centre for Transplantation, King's College London, Great Maze Pond, London, SE1 9RT, UK. s.christakoudi@imperial.ac.uk.

Konstantinos K Tsilidis (KK)

Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, St Mary's Campus, London, W2 1PG, UK.
Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, 45100, Ioannina, Greece.

David C Muller (DC)

Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, St Mary's Campus, London, W2 1PG, UK.

Heinz Freisling (H)

International Agency for Research on Cancer, World Health Organization, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France.

Elisabete Weiderpass (E)

International Agency for Research on Cancer, World Health Organization, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France.

Kim Overvad (K)

Department of Public Health, Aarhus University, DK-8000, Aarhus, Denmark.
Department of Cardiology, Aalborg University Hospital, DK-9000, Aalborg, Denmark.

Stefan Söderberg (S)

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Christel Häggström (C)

Department of Biobank Research, Umeå University, Umeå, Sweden.
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Tobias Pischon (T)

Max Delbrück Center for Molecular Medicine, 13125, Berlin, Germany.
Charité - Universitätsmedizin Berlin, Berlin, Germany.
Berlin Institute of Health (BIH), Berlin, Germany.

Christina C Dahm (CC)

Department of Public Health, Aarhus University, DK-8000, Aarhus, Denmark.

Jie Zhang (J)

Department of Public Health, Aarhus University, DK-8000, Aarhus, Denmark.

Anne Tjønneland (A)

Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen Ø, Denmark.
Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Jytte Halkjær (J)

Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100, Copenhagen Ø, Denmark.

Conor MacDonald (C)

Centre de recherche en Epidemiologie et Sante des Populations (CESP), Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris-Saclay, 94805, Villejuif, France.
Gustave Roussy, F-94805, Villejuif, France.

Marie-Christine Boutron-Ruault (MC)

Centre de recherche en Epidemiologie et Sante des Populations (CESP), Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris-Saclay, 94805, Villejuif, France.
Gustave Roussy, F-94805, Villejuif, France.

Francesca Romana Mancini (FR)

Centre de recherche en Epidemiologie et Sante des Populations (CESP), Fac. de médecine - Univ. Paris-Sud, Fac. de médecine - UVSQ, INSERM, Université Paris-Saclay, 94805, Villejuif, France.
Gustave Roussy, F-94805, Villejuif, France.

Tilman Kühn (T)

German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany.

Rudolf Kaaks (R)

German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany.

Matthias B Schulze (MB)

Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Institute of Nutritional Sciences, University of Potsdam, Nuthetal, Germany.

Antonia Trichopoulou (A)

Hellenic Health Foundation, Athens, Greece.

Anna Karakatsani (A)

Hellenic Health Foundation, Athens, Greece.
2nd Pulmonary Medicine Department, School of Medicine, National and Kapodistrian University of Athens, "ATTIKON" University Hospital, Haidari, Greece.

Eleni Peppa (E)

Hellenic Health Foundation, Athens, Greece.

Giovanna Masala (G)

Cancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network - ISPRO, Florence, Italy.

Valeria Pala (V)

Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via Venezian, 1, 20133, Milan, Italy.

Salvatore Panico (S)

Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy.

Rosario Tumino (R)

Cancer Registry and Histopathology Department, Azienda Sanitaria Provinciale Ragusa (ASP), Ragusa, Italy.

Carlotta Sacerdote (C)

Unit of Cancer Epidemiology, Città della Salute e della Scienza University-Hospital and Center for Cancer Prevention (CPO), Turin, Italy.

J Ramón Quirós (JR)

Public Health Directorate, Asturias, Spain.

Antonio Agudo (A)

Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.

Maria-Jose Sánchez (MJ)

Andalusian School of Public Health (EASP), Granada, Spain.
Instituto de Investigación Biosanitaria de Granada ibs.GRANADA, Granada, Spain.
Universidad de Granada, Granada, Spain.
CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.

Lluís Cirera (L)

CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Department of Epidemiology, Murcia Regional Health Council, IMIB - Arrixaca, Murcia, Spain.
Department of Health and Social Sciences, University of Murcia, Murcia, Spain.

Aurelio Barricarte-Gurrea (A)

CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Navarra Public Health Institute, Pamplona, Spain.
Navarra Institute for Health Research (IdiSNA) Pamplona, Pamplona, Spain.

Pilar Amiano (P)

CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Public Health Division of Gipuzkoa, BioDonostia Research Institute, San Sebastian, Spain.

Ensieh Memarian (E)

Dept. Clinical Sciences, Skane University Hospital, Lund University, 20502, Malmö, Sweden.

Emily Sonestedt (E)

Nutritional Epidemiology, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.

Bas Bueno-de-Mesquita (B)

Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, St Mary's Campus, London, W2 1PG, UK.
Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA, Bilthoven, The Netherlands.
Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands.
Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Pantai Valley, 50603, Kuala Lumpur, Malaysia.

Anne M May (AM)

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, STR 6.131, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

Kay-Tee Khaw (KT)

School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 2QQ, UK.

Nicholas J Wareham (NJ)

MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK.

Tammy Y N Tong (TYN)

Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Inge Huybrechts (I)

International Agency for Research on Cancer, World Health Organization, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France.

Hwayoung Noh (H)

International Agency for Research on Cancer, World Health Organization, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France.

Elom K Aglago (EK)

International Agency for Research on Cancer, World Health Organization, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France.

Merete Ellingjord-Dale (M)

Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, St Mary's Campus, London, W2 1PG, UK.

Heather A Ward (HA)

Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, St Mary's Campus, London, W2 1PG, UK.

Dagfinn Aune (D)

Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, St Mary's Campus, London, W2 1PG, UK.
Department of Nutrition, Bjørknes University College, Oslo, Norway.
Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.

Elio Riboli (E)

Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, St Mary's Campus, London, W2 1PG, UK.

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Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Biométrie › Anthropométrie › Indice de masse corporelle › A Body Shape Index (ABSI) achieves better...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › A Body Shape Index (ABSI) achieves better...
questionsmedicales.fr › Régions géographiques › Europe › A Body Shape Index (ABSI) achieves better...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A Body Shape Index (ABSI) achieves better...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › Obésité abdominale › A Body Shape Index (ABSI) achieves better...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de survie › Modèles des risques proportionnels › A Body Shape Index (ABSI) achieves better...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › A Body Shape Index (ABSI) achieves better...
questionsmedicales.fr › Phénomènes physiologiques › Constitution physique › Poids et mesures du corps › Tour de taille › A Body Shape Index (ABSI) achieves better...
questionsmedicales.fr › Phénomènes physiologiques › Constitution physique › Poids et mesures du corps › Rapport taille-hanches › A Body Shape Index (ABSI) achieves better...