A Novel Quantitative Index of Meibomian Gland Dysfunction, the Meibomian Gland Tortuosity.
asymptomatic MGD
diagnosis
meibomian gland dysfunction
meibomian gland tortuosity
symptomatic MGD
Journal
Translational vision science & technology
ISSN: 2164-2591
Titre abrégé: Transl Vis Sci Technol
Pays: United States
ID NLM: 101595919
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
27
02
2020
accepted:
10
07
2020
entrez:
5
9
2020
pubmed:
5
9
2020
medline:
5
9
2020
Statut:
epublish
Résumé
To quantitatively measure meibomian gland (MG) tortuosity in meibomian gland dysfunction (MGD) patients and normal controls and to observe the efficacy of evaluating MG tortuosity for the diagnosis of MGD. This cross-sectional study enrolled 32 obstructive MGD patients and 28 normal volunteers. Clinical assessments were performed, including symptom questionnaires, tear meniscus height, tear break-up time (TBUT), corneal fluorescein staining, lid margin abnormality, MG expressibility, and meibography. The meibomian gland tortuosity and meibomian gland density were measured by VIA software. The mean age of the patients in the MGD group was 33.28 ± 9.28 years, and that of the normal controls was 25.25 ± 11.19 years. The average tortuosity of all MGs in the MGD patients was significantly larger than in the normal controls ( MG tortuosity is an effective index to delineate MG morphology and to diagnose MGD, especially for the diagnosis of early-stage MGD. Calculating tortuosity quantitatively may play an important role in the diagnosis of MGD.
Identifiants
pubmed: 32884858
doi: 10.1167/tvst.9.9.34
pii: TVST-20-2386
pmc: PMC7445362
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Pagination
34Informations de copyright
Copyright 2020 The Authors.
Déclaration de conflit d'intérêts
Disclosure: X. Lin, None; Y. Fu, None; L. Li, None; C. Chen, None; X. Chen, None; Y. Mao, None; H. Lian, None; W. Yang, None; Q. Dai, None
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