Duodenal Duplication Cysts in Children: Clinical Features and Current Treatment Choices.

Duodenal duplication cyst Endoscopy Imaging Pediatrics Surgery

Journal

Biomedicine hub
ISSN: 2296-6870
Titre abrégé: Biomed Hub
Pays: Switzerland
ID NLM: 101692630

Informations de publication

Date de publication:
Historique:
received: 05 03 2020
accepted: 04 05 2020
entrez: 5 9 2020
pubmed: 5 9 2020
medline: 5 9 2020
Statut: epublish

Résumé

Duodenal duplication cysts are rare gastrointestinal tract malformations. Most patients experience symptom onset in the first decade of life. This review aims to examine clinical presentation, management strategies and outcomes of duodenal duplication cysts in childhood. A Pubmed/Medline (http://www.ncbi.nlm.nih.gov/pubmed/) search in October 2019 for articles published since 1999 using the keywords "duodenal duplication cyst," "child" and "newborn" was carried out. Clinical symptoms, complications, diagnostic examinations, treatment options and outcomes were analyzed and tabulated. There were 41 citations in the literature providing adequate descriptions of 45 cases of duodenal duplication cysts. The age of presentation ranged from newborn to 18 years. The median interval between initial presentation and definitive diagnosis and treatment was 17 months (range: 2 months to 12 years). Overall, 67% of cases presented with abdominal pain, and 43% were complicated with pancreatitis. Different surgical and endoscopic therapeutic strategies were reported. Duodenal duplication cysts may be associated with life-threatening complications and/or recurrent symptoms, impairing quality of life. Early recognition of patients who demonstrate suggestive signs and symptoms is important to ensure success of treatment. This review may be useful to highlight the main diagnostic aspects and limit the risk of a delayed diagnosis.

Sections du résumé

BACKGROUND BACKGROUND
Duodenal duplication cysts are rare gastrointestinal tract malformations. Most patients experience symptom onset in the first decade of life. This review aims to examine clinical presentation, management strategies and outcomes of duodenal duplication cysts in childhood.
METHODS METHODS
A Pubmed/Medline (http://www.ncbi.nlm.nih.gov/pubmed/) search in October 2019 for articles published since 1999 using the keywords "duodenal duplication cyst," "child" and "newborn" was carried out. Clinical symptoms, complications, diagnostic examinations, treatment options and outcomes were analyzed and tabulated.
RESULTS RESULTS
There were 41 citations in the literature providing adequate descriptions of 45 cases of duodenal duplication cysts. The age of presentation ranged from newborn to 18 years. The median interval between initial presentation and definitive diagnosis and treatment was 17 months (range: 2 months to 12 years). Overall, 67% of cases presented with abdominal pain, and 43% were complicated with pancreatitis. Different surgical and endoscopic therapeutic strategies were reported.
CONCLUSIONS CONCLUSIONS
Duodenal duplication cysts may be associated with life-threatening complications and/or recurrent symptoms, impairing quality of life. Early recognition of patients who demonstrate suggestive signs and symptoms is important to ensure success of treatment. This review may be useful to highlight the main diagnostic aspects and limit the risk of a delayed diagnosis.

Identifiants

DOI: 10.1159/000508489 PMID: 32884929 PMC: PMC7443659
pubmed: 32884929
doi: 10.1159/000508489
pii: bmh-0005-0152
pmc: PMC7443659
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

152-164

Informations de copyright

Copyright © 2020 by S. Karger AG, Basel.

Déclaration de conflit d'intérêts

The authors have no conflicts of interest to declare. The authors have no financial interests.

Références

J Pediatr Surg. 2005 Sep;40(9):e37-40
pubmed: 16150332
J Pediatr Surg. 2013 Apr;48(4):e25-8
pubmed: 23583161
Pediatr Surg Int. 2005 Apr;21(4):320-2
pubmed: 15723222
APSP J Case Rep. 2012 May;3(2):15
pubmed: 22953309
J Clin Ultrasound. 2008 Nov-Dec;36(9):584-6
pubmed: 18393380
VideoGIE. 2018 Sep 26;3(11):356-357
pubmed: 30402584
APSP J Case Rep. 2012 Sep;3(3):19
pubmed: 23061035
Pediatr Surg Int. 2006 May;22(5):456-8
pubmed: 16552575
World J Gastroenterol. 2014 Jan 28;20(4):1123-6
pubmed: 24574788
J Pediatr Surg. 2002 May;37(5):E8
pubmed: 11987108
European J Pediatr Surg Rep. 2015 Dec;3(2):82-4
pubmed: 26788454
Endoscopy. 2009;41 Suppl 2:E32-3
pubmed: 19288421
J Paediatr Child Health. 2017 Aug;53(8):814-816
pubmed: 28695671
J Neonatal Surg. 2014 Jan 01;3(1):11
pubmed: 26023482
J Pediatr Surg. 2012 Nov;47(11):e33-5
pubmed: 23164028
Endosc Ultrasound. 2014 Jul;3(3):152-60
pubmed: 25184121
Pediatr Radiol. 2002 Feb;32(2):124-5
pubmed: 11819082
J Clin Ultrasound. 2013 Nov-Dec;41 Suppl 1:1-5
pubmed: 23124691
J Pediatr Surg. 1999 Apr;34(4):645-8
pubmed: 10235345
Pediatr Neonatol. 2009 Aug;50(4):169-72
pubmed: 19750892
J Pediatr Surg. 2009 Jan;44(1):e33-5
pubmed: 19159708
Br J Surg. 1995 Jan;82(1):74-8
pubmed: 7881964
Pediatr Neonatol. 2017 Apr;58(2):194-195
pubmed: 27663362
Eur J Pediatr Surg. 2010 Mar;20(2):125-8
pubmed: 19530069
Eur J Pediatr Surg. 2006 Feb;16(1):18-23
pubmed: 16544221
Can J Gastroenterol. 2000 Apr;14(4):341-5
pubmed: 10799089
J Pediatr Surg. 1999 Aug;34(8):1297-9
pubmed: 10466620
J Clin Ultrasound. 2002 Nov-Dec;30(9):566-8
pubmed: 12404525
Gastrointest Endosc. 2005 Jul;62(1):190-2
pubmed: 15990852
J Pediatr Surg. 2007 Dec;42(12):e21-2
pubmed: 18082686
Gastrointest Endosc. 2008 Jan;67(1):163-8
pubmed: 18155438
J Pediatr Surg. 2010 Aug;45(8):1598-606
pubmed: 20713206
Eur J Surg. 2000 Jun;166(6):504-7
pubmed: 10890551
Eur J Pediatr Surg. 2000 Jun;10(3):201-3
pubmed: 10982053
Surg Oncol. 2012 Dec;21(4):324-30
pubmed: 23025911
J Pediatr Surg. 2011 May;46(5):874-8
pubmed: 21616244
Biol Neonate. 2002;81(3):210-2
pubmed: 11937728
Minerva Chir. 2001 Jun;56(3):317-9
pubmed: 11423800
Surg Today. 2004;34(5):459-62
pubmed: 15108090
World J Gastroenterol. 2006 Mar 14;12(10):1630-3
pubmed: 16570360
Pediatr Radiol. 2001 Mar;31(3):187-8
pubmed: 11297084
Prenat Diagn. 2004 Apr;24(4):312-4
pubmed: 15065109
Pediatr Surg Int. 2000;16(7):517-8
pubmed: 11057557
Surg Today. 2005;35(7):586-9
pubmed: 15976957
J Med Case Rep. 2013 Mar 14;7:70
pubmed: 23497458
J Pediatr Gastroenterol Nutr. 2002 Sep;35(3):372-6
pubmed: 12352532
J Pediatr. 2013 Oct;163(4):1224-1224.e1
pubmed: 23684110
Pediatr Surg Int. 2012 Oct;28(10):1035-9
pubmed: 22752148
Surgery. 2001 Jul;130(1):112-5
pubmed: 11436024

Auteurs

Valeria Dipasquale (V)

Pediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adulthood and Childhood G. Barresi, University Hospital of Messina, Messina, Italy.

Paolo Barraco (P)

Pediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adulthood and Childhood G. Barresi, University Hospital of Messina, Messina, Italy.

Simona Faraci (S)

Digestive Endoscopy and Surgery Unit, Children's Hospital Bambino Gesù, Rome, Italy.

Valerio Balassone (V)

Digestive Endoscopy and Surgery Unit, Children's Hospital Bambino Gesù, Rome, Italy.

Paola De Angelis (P)

Digestive Endoscopy and Surgery Unit, Children's Hospital Bambino Gesù, Rome, Italy.

Francesco Maria Di Matteo (FM)

Digestive Endoscopy Unit, Campus Bio-Medico, University of Rome, Rome, Italy.

Luigi Dall'Oglio (L)

Digestive Endoscopy and Surgery Unit, Children's Hospital Bambino Gesù, Rome, Italy.

Claudio Romano (C)

Pediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adulthood and Childhood G. Barresi, University Hospital of Messina, Messina, Italy.

Classifications MeSH