Relative content detection of oligomannose modification of IgM heavy chain induced by TNP-antigen in an early vertebrate through nanoLC-MS/MS.
Antigen recognition
IgM
Oligomannose
Oreochromis niloticus
nanoLC-MS/MS
Journal
Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R
Informations de publication
Date de publication:
01 Nov 2020
01 Nov 2020
Historique:
received:
20
04
2020
revised:
20
06
2020
accepted:
24
06
2020
entrez:
5
9
2020
pubmed:
6
9
2020
medline:
15
5
2021
Statut:
ppublish
Résumé
N-glycan modification is reported to be important in regulating the structure and function of immunoglobulins in mammals. While, the study on teleost immunoglobulin glycosylation is still limitted. In this study, we constructed a TNP-antigen driven model, and detected the site-specific N-glycans of PBS-immunized and TNP-specific Oreochromis niloticus serum IgM through
Identifiants
pubmed: 32887075
pii: S0039-9140(20)30637-8
doi: 10.1016/j.talanta.2020.121346
pii:
doi:
Substances chimiques
Immunoglobulin M
0
Polysaccharides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
121346Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.