Iridocorneal Angle Assessment After Laser Iridotomy With Swept-source Optical Coherence Tomography.


Journal

Journal of glaucoma
ISSN: 1536-481X
Titre abrégé: J Glaucoma
Pays: United States
ID NLM: 9300903

Informations de publication

Date de publication:
11 2020
Historique:
pubmed: 6 9 2020
medline: 6 3 2021
entrez: 5 9 2020
Statut: ppublish

Résumé

To investigate the reliability of anterior chamber angle (ACA) measurements in narrow angles and assess the effect of laser peripheral iridotomy (LPI) on these measurements using novel swept-source optical coherence tomography (SS-OCT) technology. In this prospective observational study, patients with gonioscopically narrow angles were enrolled and scheduled for prophylactic LPI. Twelve ACA sections were obtained in each eye using SS-OCT (ANTERION, Heidelberg Engineering, Germany) before and after Nd:YAG LPI. A built-in algorithm calculated ACA measurements after manual identification of the scleral spur and ACA recess. Eight ACA parameters were evaluated: ACA (ACA 500, ACA 750); scleral spur angle (SSA 500, SSA 750); angle opening distance (AOD 500, AOD 750); and trabecular iris space area (TISA 500, TISA 750). The effect of LPI was assessed for each parameter, both nasally and temporally. Ten patients (18 eyes) were enrolled (mean age, 61.8±13.6 y; 60.0% female individuals). On average, the ACA was wider nasally than temporally (P=0.004). LPI significantly widened the ACA (range, 26.7-29.4%; P<0.05). ACA 500 increased by 29.4% (P<0.001), ACA 750 by 29.2% (P=0.002), SSA 500 by 27.3% (P=0.003), SSA 750 by 28.1% (P=0.001), AOD 500 by 28.6% (P=0.009), AOD 750 by 28.6% (P=0.003), TISA 500 by 27.3% (P=0.004), and TISA 750 by 26.7% (P=0.200). SS-OCT ANTERION imaging can be used to reliably measure ACA before and after LPI. ACA, AOD, SSA, and TISA are all valid ACA measurement methods.

Identifiants

pubmed: 32890108
doi: 10.1097/IJG.0000000000001654
pii: 00061198-202011000-00005
doi:

Banques de données

ClinicalTrials.gov
['NCT04381611']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1030-1035

Références

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Auteurs

Enrico Meduri (E)

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.

Kevin Gillmann (K)

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.

Giorgio E Bravetti (GE)

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.

Letitia J Niegowski (LJ)

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.

André Mermoud (A)

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.

Robert N Weinreb (RN)

Viterbi Family Department of Ophthalmology, Shiley Eye Institute, Hamilton Glaucoma Center, University of California, San Diego, CA.

Kaweh Mansouri (K)

Glaucoma Research Center, Montchoisi Clinic, Swiss Visio, Lausanne, Switzerland.
Department of Ophthalmology, University of Colorado School of Medicine, Denver, CO.

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