Pyuria without Casts and Bilateral Kidney Enlargement Are Probable Hallmarks of Severe Acute Kidney Injury Induced by Acute Pyelonephritis: A Case Report and Literature Review.


Journal

Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241

Informations de publication

Date de publication:
15 Jan 2021
Historique:
pubmed: 8 9 2020
medline: 15 4 2021
entrez: 7 9 2020
Statut: ppublish

Résumé

The patient was a 38-year-old man who had experienced nausea and fever for a few days and presented with back pain, oliguria, and pyuria, suggesting acute pyelonephritis (APN). He showed acute kidney injury (AKI) with bilateral kidney enlargement and was using nonsteroidal anti-inflammatory drugs (NSAIDs). AKI-induced by APN was confirmed by kidney biopsy. The AKI was successfully treated with antibiotic therapy. A search of the relevant literature for reports on histopathologically-proven APN-induced severe AKI revealed that the key characteristics were bilateral kidney enlargement with pyuria without casts. Oligoanuria was frequently associated with APN-induced severe AKI, and NSAID use may be a possible risk factor. Prompt antibiotic treatment based on the clinical characteristics of APN-induced AKI can improve the renal outcome.

Identifiants

pubmed: 32893233
doi: 10.2169/internalmedicine.5721-20
pmc: PMC7872795
doi:

Substances chimiques

Anti-Inflammatory Agents, Non-Steroidal 0

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

293-298

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Auteurs

Kohei Odajima (K)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Ryo Togashi (R)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Yoshikazu Nemoto (Y)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Yuto Hayama (Y)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Shinichiro Asakawa (S)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Michito Nagura (M)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Shigeyuki Arai (S)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Osamu Yamazaki (O)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Yoshifuru Tamura (Y)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Makoto Mochizuki (M)

Department of Clinical Laboratory Science, Faculty of Medical Technology, Teikyo University, Japan.

Ryuji Ohashi (R)

Department of Integrated Diagnostic Pathology, Nippon Medical School, Japan.

Shigeru Shibata (S)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

Yoshihide Fujigaki (Y)

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

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