RAB6 GTPase regulates mammary secretory function by controlling the activation of STAT5.

Animals Blotting, Western Cell Line Female Flow Cytometry Humans In Situ Nick-End Labeling Mammary Glands, Human / cytology Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic STAT5 Transcription Factor / genetics rab GTP-Binding Proteins / genetics
Luminal secretory cells Mammary gland PRL signaling RAB6 GTPase STAT5

Journal

Development (Cambridge, England)
ISSN: 1477-9129
Titre abrégé: Development
Pays: England
ID NLM: 8701744

Informations de publication

Date de publication:
08 10 2020
Historique:
received: 18 03 2020
accepted: 19 08 2020
pubmed: 9 9 2020
medline: 10 4 2021
entrez: 8 9 2020
Statut: epublish

Résumé

The Golgi-associated RAB GTPases, RAB6A and RAB6A', regulate anterograde and retrograde transport pathways from and to the Golgi.

Identifiants

DOI: 10.1242/dev.190744 PMID: 32895290 PMC: PMC7561474
pubmed: 32895290
pii: dev.190744
doi: 10.1242/dev.190744
pmc: PMC7561474
pii:
doi:

Substances chimiques

STAT5 Transcription Factor 0
rab GTP-Binding Proteins EC 3.6.5.2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2020. Published by The Company of Biologists Ltd.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing or financial interests.

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Auteurs

Surya Cayre (S)

Department of Cell Biology and Cancer, Institut Curie, PSL Research University, Sorbonne Université, CNRS, UMR144, Paris F-75005, France.

Marisa M Faraldo (MM)

Department of Cell Biology and Cancer, Institut Curie, PSL Research University, Sorbonne Université, CNRS, UMR144, Paris F-75005, France.
INSERM, Paris F-75013, France.
ORCID: 0000-0001-9497-1171

Sabine Bardin (S)

Department of Cell Biology and Cancer, Institut Curie, PSL Research University, Sorbonne Université, CNRS, UMR144, Paris F-75005, France.

Stéphanie Miserey-Lenkei (S)

Department of Cell Biology and Cancer, Institut Curie, PSL Research University, Sorbonne Université, CNRS, UMR144, Paris F-75005, France.
ORCID: 0000-0003-4994-0258

Marie-Ange Deugnier (MA)

Department of Cell Biology and Cancer, Institut Curie, PSL Research University, Sorbonne Université, CNRS, UMR144, Paris F-75005, France marie-ange.deugnier@curie.fr bruno.goud@curie.fr.
INSERM, Paris F-75013, France.
ORCID: 0000-0002-2199-1099

Bruno Goud (B)

Department of Cell Biology and Cancer, Institut Curie, PSL Research University, Sorbonne Université, CNRS, UMR144, Paris F-75005, France marie-ange.deugnier@curie.fr bruno.goud@curie.fr.
ORCID: 0000-0003-1227-4159

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › RAB6 GTPase regulates mammary secretory...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Dosage immunologique › Immunotransfert › Technique de Western › RAB6 GTPase regulates mammary secretory...
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › RAB6 GTPase regulates mammary secretory...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Cytophotométrie › Cytométrie en flux › RAB6 GTPase regulates mammary secretory...
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questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Méthode TUNEL › RAB6 GTPase regulates mammary secretory...
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questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › RAB6 GTPase regulates mammary secretory...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › RAB6 GTPase regulates mammary secretory...
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