WASh multicentre randomised controlled trial: water-assisted sigmoidoscopy in English NHS bowel scope screening.
clinical trials
colorectal cancer screening
colorectal neoplasia
gastrointesinal endoscopy
Journal
Gut
ISSN: 1468-3288
Titre abrégé: Gut
Pays: England
ID NLM: 2985108R
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
20
05
2020
revised:
29
07
2020
accepted:
03
08
2020
pubmed:
9
9
2020
medline:
15
12
2021
entrez:
8
9
2020
Statut:
ppublish
Résumé
The English Bowel Cancer Screening Programme invites 55 year olds for a sigmoidoscopy (Bowel Scope Screening (BSS)), aiming to resect premalignant polyps, thus reducing cancer incidence. A national patient survey indicated higher procedural pain than anticipated, potentially impacting on screening compliance and effectiveness. We aimed to assess whether water-assisted sigmoidoscopy (WAS), as opposed to standard CO The WASh (Water-Assisted Sigmoidoscopy) trial was a multicentre, single-blind, randomised control trial for people undergoing BSS. Participants were randomised to either receive WAS or CO 1123 participants (50% women, mean age 55) were randomised (561 WAS, 562 CO In the context of enema-prepared unsedated screening sigmoidoscopies performed by screening-accredited endoscopists, no difference in patient-reported pain was seen when using either a CO ISRCTN81466870.
Identifiants
pubmed: 32895334
pii: gutjnl-2020-321918
doi: 10.1136/gutjnl-2020-321918
pmc: PMC8040154
doi:
Substances chimiques
Water
059QF0KO0R
Banques de données
ISRCTN
['ISRCTN81466870']
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
845-852Subventions
Organisme : Department of Health
ID : PB-PG-1215-20035
Pays : United Kingdom
Investigateurs
Mike Bramble
(M)
Anjan Dhar
(A)
Stuart Riley
(S)
Tony Larkin
(T)
Sophie Whyte
(S)
Adetayo Kasim
(A)
Andrew Veitch
(A)
Andrew Chilton
(A)
Ben Carter Lynne Williams
(BCL)
Jane Greenaway
(J)
Justin Carter
(J)
Vicky Collins
(V)
Clare Westwood
(C)
Tom Lee
(T)
Sarah Crane
(S)
James MacBain
(J)
Catherine Lawrence
(C)
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Type : CommentIn
Informations de copyright
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: MDR reports personal fees from Swiss SCWeb, personal fees from Pentax, grants from Olympus and personal fees from Norgine, outside the submitted work. ZPT reports other from Creo Medical Ltd, grants from Norgine Ltd, other from Olympus KeyMed and Pentax Medical, outside the submitted work. CJR reports grant funding from ARC Medical, Norgine and Olympus Medical, and was an expert witness for ARC Medical.
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