Click-Free Synthesis of a Multivalent Tricyclic Peptide as a Molecular Transporter.

MDA-MB-231 antibacterial activity cell-penetrating peptide cellular uptake cyclic peptide cytotoxicity drug delivery phosphopeptide siRNA tricyclic

Journal

Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003

Informations de publication

Date de publication:
03 Sep 2020
Historique:
received: 08 08 2020
revised: 29 08 2020
accepted: 31 08 2020
entrez: 9 9 2020
pubmed: 10 9 2020
medline: 10 9 2020
Statut: epublish

Résumé

The cellular delivery of cell-impermeable and water-insoluble molecules remains an ongoing challenge to overcome. Previously, we reported amphipathic cyclic peptides

Identifiants

pubmed: 32899170
pii: pharmaceutics12090842
doi: 10.3390/pharmaceutics12090842
pmc: PMC7558522
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Sumit Kumar (S)

Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University School of Pharmacy, Irvine, CA 92618, USA.
Department of Chemistry, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, Haryana 131039, India.

Dindyal Mandal (D)

Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University School of Pharmacy, Irvine, CA 92618, USA.
School of Biotechnology, KIIT Deemed to be University, Bhubaneswar 751024, India.

Shaima Ahmed El-Mowafi (SA)

Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University School of Pharmacy, Irvine, CA 92618, USA.
Peptide Chemistry Department, National Research Centre, Dokki, Cairo 12622, Egypt.

Saghar Mozaffari (S)

Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University School of Pharmacy, Irvine, CA 92618, USA.

Rakesh Kumar Tiwari (RK)

Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University School of Pharmacy, Irvine, CA 92618, USA.

Keykavous Parang (K)

Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University School of Pharmacy, Irvine, CA 92618, USA.

Classifications MeSH