Electrosprayed Chitin Nanofibril/Electrospun Polyhydroxyalkanoate Fiber Mesh as Functional Nonwoven for Skin Application.
anti-inflammatory
bio-based
biopolymer
electrospinning
electrospray
nanolignin
surface modification
Journal
Journal of functional biomaterials
ISSN: 2079-4983
Titre abrégé: J Funct Biomater
Pays: Switzerland
ID NLM: 101570734
Informations de publication
Date de publication:
03 Sep 2020
03 Sep 2020
Historique:
received:
20
07
2020
revised:
19
08
2020
accepted:
24
08
2020
entrez:
9
9
2020
pubmed:
10
9
2020
medline:
10
9
2020
Statut:
epublish
Résumé
Polyhydroxyalkanoates (PHAs) are a family of bio-based polyesters that have found different biomedical applications. Chitin and lignin, byproducts of fishery and plant biomass, show antimicrobial and anti-inflammatory activity on the nanoscale. Due to their polarities, chitin nanofibril (CN) and nanolignin (NL) can be assembled into micro-complexes, which can be loaded with bioactive factors, such as the glycyrrhetinic acid (GA) and CN-NL/GA (CLA) complexes, and can be used to decorate polymer surfaces. This study aims to develop completely bio-based and bioactive meshes intended for wound healing. Poly(3-hydroxybutyrate)/Poly(3-hydroxyoctanoate-co-3-hydroxydecanoate), P(3HB)/P(3HO-
Identifiants
pubmed: 32899241
pii: jfb11030062
doi: 10.3390/jfb11030062
pmc: PMC7565933
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Bio-Based Industries Joint Undertaking - European Union Horizon 2020 research program (BBI-H2020)
ID : PolyBioSkin (G.A. 745839)
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