Analysis of the Subgingival Microbiota in Implant-Supported Full-Arch Rehabilitations.
dental implants
full-arch
microbiota
peri-implant
peri-implantitis
prosthesis
Journal
Dentistry journal
ISSN: 2304-6767
Titre abrégé: Dent J (Basel)
Pays: Switzerland
ID NLM: 101716125
Informations de publication
Date de publication:
05 Sep 2020
05 Sep 2020
Historique:
received:
18
08
2020
revised:
31
08
2020
accepted:
03
09
2020
entrez:
9
9
2020
pubmed:
10
9
2020
medline:
10
9
2020
Statut:
epublish
Résumé
The etiology of peri-implantitis is multifactorial, and it is not directly linked to the quantitative amount of plaque. The aim of this study was to evaluate the influence of subgingival microbiota around implants supporting full-arch restorations on clinical indexes of peri-implant health. 47 patients (54 full-arch fixed rehabilitations) were included. Based on the highest value of probing depth (PD), 47 implants (in the test arch), 40 natural teeth and 7 implants (in the antagonist arch) were selected for microbiological sampling (traditional PCR and real-time PCR). Periodontal indexes (plaque index, PlI; probing depth, PD; bleeding on probing, BOP; peri-implant suppuration, PS) and marginal bone loss were also recorded. Despite abundant plaque accumulation, the peri-implant parameters were within normal limits. No statistical difference was found in the microbial population around the test implants and antagonist natural teeth. Treponema denticola was present in a significantly higher amount around implants with increased PlI. Implants with increased BOP showed a significant increase in Treponema denticola and Tannerella forsythia. A significantly higher presence of Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia was identified around the implants affected by peri-implantitis and in smokers. Peri-implantitis is characterized by a complex and polymicrobial disease, that might be influenced by the qualitative profile of plaque. Smoking might also favor implant biological complications in full-arch fixed prosthesis.
Sections du résumé
BACKGROUND
BACKGROUND
The etiology of peri-implantitis is multifactorial, and it is not directly linked to the quantitative amount of plaque. The aim of this study was to evaluate the influence of subgingival microbiota around implants supporting full-arch restorations on clinical indexes of peri-implant health.
METHOD
METHODS
47 patients (54 full-arch fixed rehabilitations) were included. Based on the highest value of probing depth (PD), 47 implants (in the test arch), 40 natural teeth and 7 implants (in the antagonist arch) were selected for microbiological sampling (traditional PCR and real-time PCR). Periodontal indexes (plaque index, PlI; probing depth, PD; bleeding on probing, BOP; peri-implant suppuration, PS) and marginal bone loss were also recorded.
RESULTS
RESULTS
Despite abundant plaque accumulation, the peri-implant parameters were within normal limits. No statistical difference was found in the microbial population around the test implants and antagonist natural teeth. Treponema denticola was present in a significantly higher amount around implants with increased PlI. Implants with increased BOP showed a significant increase in Treponema denticola and Tannerella forsythia. A significantly higher presence of Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia was identified around the implants affected by peri-implantitis and in smokers.
CONCLUSIONS
CONCLUSIONS
Peri-implantitis is characterized by a complex and polymicrobial disease, that might be influenced by the qualitative profile of plaque. Smoking might also favor implant biological complications in full-arch fixed prosthesis.
Identifiants
pubmed: 32899493
pii: dj8030104
doi: 10.3390/dj8030104
pmc: PMC7557827
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Sci Rep. 2014 Oct 13;4:6602
pubmed: 25308100
J Med Microbiol. 2018 Mar;67(3):332-340
pubmed: 29458668
J Dent Res. 2015 Sep;94(9):1202-17
pubmed: 26124222
J Periodontol. 2017 Oct;88(10):1066-1089
pubmed: 28625077
Clin Oral Implants Res. 2016 Mar;27(3):376-82
pubmed: 25622536
Clin Implant Dent Relat Res. 2014 Dec;16(6):783-93
pubmed: 23527870
Int J Prosthodont. 2014 May-Jun;27(3):207-14
pubmed: 24905260
Compend Contin Educ Dent. 2017 Sep;38(8 Suppl):22-25
pubmed: 29227113
Clin Oral Implants Res. 2002 Aug;13(4):349-58
pubmed: 12175371
Int J Oral Maxillofac Implants. 2017 May 18;32(4):774–778
pubmed: 28518179
Clin Oral Investig. 2019 Aug;23(8):3161-3171
pubmed: 30386996
J Clin Med. 2019 Jun 21;8(6):
pubmed: 31234311
Int J Oral Maxillofac Implants. 2017 Sep/Oct;32(5):1054-1064
pubmed: 28906504
J Dent. 2012 Nov;40(11):989-98
pubmed: 22917562
Clin Oral Implants Res. 1999 Oct;10(5):339-45
pubmed: 10551058
J Clin Periodontol. 1998 Feb;25(2):134-44
pubmed: 9495612
Int J Oral Maxillofac Implants. 2016 Mar-Apr;31(2):359-68
pubmed: 26478978
Dent J (Basel). 2015 Mar 31;3(2):24-42
pubmed: 29567923
Int J Prosthodont. 2018 Jul/Aug;31(4):327-333
pubmed: 29953561
J Oral Maxillofac Res. 2016 Sep 9;7(3):e10
pubmed: 27833735
J Clin Periodontol. 2018 Jun;45 Suppl 20:S286-S291
pubmed: 29926491
Clin Oral Implants Res. 2001 Jun;12(3):189-95
pubmed: 11359474
J Clin Periodontol. 2008 Sep;35(8 Suppl):282-5
pubmed: 18724855
Arch Oral Biol. 2017 Nov;83:145-152
pubmed: 28780383
J Oral Maxillofac Res. 2016 Sep 9;7(3):e3
pubmed: 27833728
Int J Oral Maxillofac Implants. 2015 May-Jun;30(3):583-7
pubmed: 26009909
Int J Prosthodont. 2014 Jan-Feb;27(1):15-25
pubmed: 24392473
J Periodontal Res. 2018 Dec;53(6):983-991
pubmed: 30259511
Clin Oral Implants Res. 2017 Sep;28(9):e121-e134
pubmed: 27492799
Int J Prosthodont. 2019 Jan/Feb;32(1):27-31
pubmed: 30677109
Mol Oral Microbiol. 2014 Dec;29(6):248-57
pubmed: 24976068
Int J Oral Implantol (Berl). 2019;12(2):169-179
pubmed: 31090748
Int J Oral Maxillofac Implants. 2008 Nov-Dec;23(6):1117-22
pubmed: 19216282
Ther Clin Risk Manag. 2017 Nov 29;13:1529-1542
pubmed: 29238198