Is There a Role for Absorbable Metals in Surgery? A Systematic Review and Meta-Analysis of Mg/Mg Alloy Based Implants.

absorbable implants bone surgery magnesium (Mg) oral and maxillofacial orthopedic titanium (Ti)

Journal

Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929

Informations de publication

Date de publication:
04 Sep 2020
Historique:
received: 21 07 2020
revised: 31 08 2020
accepted: 01 09 2020
entrez: 9 9 2020
pubmed: 10 9 2020
medline: 10 9 2020
Statut: epublish

Résumé

Magnesium (Mg) alloys have received attention in the literature as potential biomaterials for use as absorbable implants in oral and maxillofacial and orthopedic surgery applications. This study aimed to evaluate the available clinical studies related to patients who underwent bone fixation (patients), and received conventional fixation (intervention), in comparison to absorbable metals (comparison), in terms of follow-up and complications (outcomes). A systematic review and meta-analysis were performed in accordance with the PRISMA statement and PROSPERO (CRD42020188654), PICO question, ROBINS-I, and ROB scales. The relative risk (RR) of complications and failures were calculated considering a confidence interval (CI) of 95%. Eight studies (three randomized clinical trial (RCT), one retrospective studies, two case-control studies, and two prospective studies) involving 468 patients, including 230 Mg screws and 213 Titanium (Ti) screws, were analyzed. The meta-analysis did not show any significant differences when comparing the use of Mg and Ti screws for complications (

Identifiants

pubmed: 32899725
pii: ma13183914
doi: 10.3390/ma13183914
pmc: PMC7558106
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Cortino Sukotjo (C)

Department of Restorative Dentistry, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA.

Tiburtino J Lima-Neto (TJ)

Oral and Maxillofacial Surgery, Department of Diagnosis and Surgery, Division of Oral and Maxillofacial Surgery, School of Dentistry, São Paulo State University-Unesp, Araçatuba, São Paulo 16015-050, Brazil.

Joel Fereira Santiago Júnior (JF)

Department of Health Sciences, Centro Universitário Sagrado Coração-UNISAGRADO, Bauru, São Paulo 16011-160, Brazil.

Leonardo P Faverani (LP)

Department of Diagnosis and Surgery, Division of Oral and Maxillofacial Surgery and Implantology, School of Dentistry, São Paulo State University-Unesp, Araçatuba, São Paulo 16015-050, Brazil.

Michael Miloro (M)

Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA.

Classifications MeSH